Background: Premature ejaculation (PME) can be defined as a lack in the normal voluntary control over ejaculation. It is the most common sexual dysfunction encountered by the male populace. In general, these patients presents with distress. Hence, a novel treatment to eliminate their problem is required. Although the role of SSRI has already been established, the high discontinuation rate and other types of sexual dysfunctions associated with SSRIs reduce their efficacy in controlling this menace. Levosulpiride is a new drug indicated in treatment of PE. Aims and Objectives: The objective is to study the efficacy of levosulpiride; paroxetine and their comparison in patients of PE. Methodology: Index of premature ejaculation (IPE) and intravaginal ejaculation latency time (IELT) were used. A total of 36 patients (18 in each group) were included. The patients were assessed at baseline; at 4 weeks’ and at 8 weeks’ interval. Results: On comparison the score of IPE in domains of ejaculation control, sexual satisfaction, and the total score of IPE were statistically significant on all the three visits. However, the distress score of IPE and the IELT score were statistically not significant between the two groups. Conclusion: No doubt both agents are efficacious in patients of PME but paroxetine is more efficacious than levosulpiride. At the same time, levosulpiride is a lesser studied and used drug hence more research should be done for it.

Background: Medical specialist/consultants are exposed to various factors such as long duty hours, call duties, academics, meetings and regulation of departmental work which has adversely affected their sleep quality. Objective: To assess sleep quality and association of body mass index with quality of sleep among medical consultants working in medical college. Method and Tool: This is a cross-sectional study and was done by convenient sampling technique. Pittsburg Sleep Quality Index (PSQI) was used as the assessment tool which categorizes sleep as good or poor according to the score. Chi-square test was applied to establish an association with the variables. Results: A total of 67 responses were obtained, of which 28 showed good sleep on PSQI. Among consultants having good quality sleep, the majority were females (n=18); aged above 40 years (n=17). No relationship was seen with BMI and chronic disease. Consultants spending more than 85% of the time in bed sleeping ( p < 0.006) and those going to bed before 10.30 pm ( p <0.026) had good sleep quality. Conclusion: Good quality of sleep was observed in females, people above 40 years and those who don't have any chronic disease, though this association of sleep quality with the factors was not significant. Going to bed early (before 10:30 pm) had a positive effect on sleep quality ( p <0.026). In general, poor sleep quality was seen among medical consultants.

Background: The impairment due to the psychiatric disorders makes the sufferer unable to become independent, therefore require long term support and care by their relatives. About 32% of years lived with disability (YLD) and about 13% of disability adjusted life-years (DALYs) is found in mental illness. Aims and Objectives: The aims were to study the socio-demographic profile, the caregiver burden and quality of life of the caregivers of the patients with different psychiatric illness. Also, to compare the burden and quality of life among caregivers of different psychiatric groups. Materials and Methods: It is a cross sectional study in which 120 caregivers of patients with psychiatric illnesses were included; divided into four groups (30 each): Anxiety, psychotic, mood and substance use disorders. After the consent, Zarit burden interview, socio demographic profile and quality of life -10 scales were used to assess the objectives. Results: The results revealed that maximum caregivers were males, and spouses in relation with the patient. Most of them were married and educated. Maximum had mild to moderate level of burden (49.1%), followed by moderate to severe level of burden in about 22.5% caregivers. Significant association was seen with the burden level. But no significant association was seen with the quality of life. Conclusion: Caregivers of the psychiatric patients have to suffer a lot and may land up into the psychiatric symptoms themselves.