Objective: We validated the Chinese version of the Ureteral Stent Symptoms Questionnaire (USSQ) in patients with an indwelling ureteric stent. Patients and Methods: The English version of the USSQ was translated into Chinese using a multi-step process by 3 urologists and 2 independent translators. The Chinese version was validated by asking 50 patients with temporary unilateral ureteral stent to complete the questionnaire at weeks 1 and 4 after stent placement. Thirty healthy individuals without a ureteral stent were also asked to complete the Chinese USSQ once. The psychometric properties of the questionnaire were analyzed. Results: After revision of the initial 2 drafts after translation, back translation, and pilot testing, a final draft was developed that underwent field testing. Psychometric analyses revealed satisfactory internal consistencies and test-retest reliability for all domains except for sexual matters. Most USSQ domains showed moderate correlations with each other. It demonstrated satisfactory discriminant validity (sensitivity to change, p < 0.05) and test-retest reliability. Analysis of the domains of the sexual matters was limited because of the small proportion of the study population for whom it was applicable. Conclusion: The Chinese version of the USSQ is a reliable and valid instrument to evaluate symptoms and health-related quality of life in Chinese patients with ureteric stents.

BackgroundTo investigate the etiology and clinical characteristics of community-acquired pneumonia (CAP) among children requiring bronchoalveolar lavage (BAL) and analyze the impact of the coronavirus disease 2019 (COVID-19) pandemic on the pathogen spectrum and clinical manifestations.MethodsChildren <14 years old hospitalized with CAP requiring BLA were enrolled between February 2019 to January 2020 and August 2021 to July 2022. Multiplex reverse transcription polymerase chain reaction (mRT-PCR) was used for pathogen detection. The demographic and clinical characteristics were compared between different pathogen-type infection groups, and before and during the COVID-19 pandemic.ResultsPathogen was detected in 91.66% (1363/1487) children.Mycoplasma pneumoniae, adenovirus and human rhinovirus were the most frequently detected pathogens. The frequency of detection of virus infections and co-infections was decreased during the pandemic, but the detection of atypical bacterial infections was increased. The clinical manifestations and the results of CT scans and fiberoptic bronchoscopy showed a significant difference between different types of pathogen infection, and lung inflammation was reduced during the COVID-19 pandemic compared with before the pandemic.ConclusionsM. pneumoniaeinfection might be the greatest pediatric disease burden leading to CAP in northern China. Wearing masks and social distancing in public places during the COVID-19 pandemic effectively reduced the transmission of respiratory viruses, but it did not reduce the infection rate ofM. pneumoniae. In addition, these interventions significantly reduced lung inflammation in children compared with before the pandemic.

This a preprint and has not been peer reviewed. Data may be preliminary.A clinical practice providing the more appropriate airway humidification methods applied on patients with severe traumatic brain injuryxiaohong yin 1 , banyou ma 2 , lei yang 2 , hua sun 2 , zhilei yun 2 , and yuxia wang 2 1 changzhou forth people's hospital 2 Affiliation not available

Reviews on the relationships between functional health and physical activity of general older adults have been well documented in literature. However, specific age range of older adults, in particular, older adults of 75 years or above, is currently under-examined. A systematic review was conducted to investigate the effects of physical activity on functional health older adults aged 75 years or above. The reviewed articles cover a variety range of functional health outcomes, including balance, muscle conditioning, joint range of motion, quadriceps strength, reaction time, gait speed, health-related quality of life, back and knee pain, muscle mass, and walking ability. In general, interventions of the reviewed articles had favorable effects on function health of older adults. While physical activity has been identified as an important determinant of functional health, the ways to engage in and accumulate sufficient daily physical activity warrant investigation. It is also important to explore interventions which enhance daily, self-driven physical activity of elderly, as normally supervised physical activity bears higher costs.