been associated with the extent of myocardial damage, re-infarction, left ventricular (LV) remodeling, and mortality. 1- 5 Regression of ST segment elevation has been used in several studies to assess the quality of reperfusion. 6-9 T he electrocardiogram (ECG) is the first-line diagnostic tool in ST elevation myocardial infarction (STEMI). The ECG is a simple and easily reproducible test, with a non-ambiguous diagnostic ability.ST segment resolution is commonly used as a marker of successful reperfusion. It is an independent prognostic parameter of subsequent adverse events in STEMI patients. In many studies, the absence of ST segment resolution has Background: Up to 25% of patients with ST elevation myocardial infarction (STEMI) have ST segment re-elevation after initial regression post-reperfusion and there are few data regarding its prognostic significance.
Objectives
To analyze the results of extracorporeal life support (ECLS) for cardiogenic shock complicating acute myocardial infarction (AMI) in a single‐center experience.
Background
Cardiogenic shock is still a leading cause of death for AMI. Conventional management carries mortality rates exceeding 50%. ECLS may be considered as a bridge to decision in the setting of AMI complicated by cardiogenic shock not responsive to standard management.
Methods
We performed an observational analysis of our local database. The primary end‐point was survival to hospital discharge. All variables were compared between survivors and nonsurvivors.
Results
Between January 2007 and December 2017, 56 patients were supported for cardiogenic shock complicating AMI. The mean age was 56.7 years and 89.3% were males. Baseline characteristics were comparable between both groups. Of the 50 primary percutaneous coronary interventions that were attempted, 44 (88.0%) were successful. Twenty‐three (41.1%) patients died during ECLS support. The complications’ rate during ECLS support was comparable between both groups. Twenty‐eight (50%) patients were successfully weaned from ECLS after a mean support of 8.7 days. Eight (14.3%) patients eventually died after weaning before hospital discharge. Five (8.9%) patients could not be weaned from ECLS and were switched to a long‐term mechanical circulatory support. Overall survival to hospital discharge was 41.1% (n = 23). Eighteen (32.1%) patients were alive after a mean follow‐up of 38.0 ± 29.9 (range, 4.2–95.4) months.
Conclusions
ECLS should be considered as a therapeutic solution in the management of AMI‐related cardiogenic shock with a satisfactory short‐ and long‐term survival.
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