This is the first clinical trial that reports the use of topical verapamil as a modulator in the healing process in the postoperative period. Based on clinical results and on the high level of reliability and statistical significance, we concluded that verapamil at a concentration of 50 µM is an excellent choice as a scar modulator; its use avoids the development of keloids and hypertrophic scars after plastic surgery.
The yellow nail syndrome is scarcely described and is characterized by dystrophic nails, pulmonary disturbances and lymphedema of extremities. A case of this syndrome is reported in an 89-year-old Brazilian woman with well-controlled diabetes mellitus and arterial hypertension. Additionally to the typical syndrome, the patient also presented pincer nails and yellow-brownish chromonychia. She was admitted because of acute abdominal symptoms associated with sigmoid diverticulitis and an adjacent abscess. The imaging studies revealed pulmonary and pleural changes, in addition to pericardial effusion. Incidentally, the features of Phrygian cap gallbladder anomaly were found. Neither diverticular disease nor gallbladder disorders have been related to yellow nail syndrome. In the present case study, the synchronism between some of these conditions could be casual; but diverticular disease, cholelithiasis, and diaphragmatic hernia are associated in the Saint's triad. MÉD UIS. 2015;28(3):387-91. Keywords: Diverticulum, Colon. Gallbladder diseases. Hernia, Hiatal.¿Síndrome de uñas amarillas, vesícula biliar en gorro frigio y tríada de Saint? Reporte de caso RESUMENEl síndrome de las uñas amarillas está poco descrito y se caracteriza por uñas distróficas, trastornos pulmonares y linfedema de las extremidades. Se presenta un caso de este síndrome en una mujer brasileña de 89 años de edad con diabetes mellitus bien controlada e hipertensión arterial. Adicionalmente al síndrome típico, la paciente presentó uñas en pinza y cromoniquia amarillo-marrón. La paciente fue admitida debido a síntomas abdominales agudos asociados con diverticulitis del sigmoide y un absceso adyacente. Los estudios de imágenes revelaron cambios pulmonares y pleurales, además de un derrame pericárdico. Incidentalmente, se encontraron anomalías características de vesícula biliar en gorro frigio. Ni la enfermedad diverticular ni los trastornos de la vesícula biliar se han relacionado con el síndrome de las uñas amarillas. En el presente estudio de caso, el sincronismo entre algunas de estas condiciones podría ser casual, pero la enfermedad diverticular, colelitiasis, y hernia hiatal se asocian a esta tríada. MÉD UIS. 2015;28(3):387-91.Palabras Clave: Divertículo del Colon. Molestias de la vesícula biliar. Hernia Hiatal.Artículo recibido el 24 de julio de 2015 y aceptado para publicación el 31 de octubre de 2015.MéD UIS. 2015;28(3):387-91 388Santos VM,
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