is a Deltaproteobacteria, ubiquitous, Gramnegative, uniflagellate, highly motile, preys on Gram-negative bacteria, recently reported predation on Gram-positive bacteria. It belongs to the BALOs group (Bdellovibrio and-like -organisms ). bdellovibrio exovores it moves quickly using its flagellum, adhering to the outer membrane, secreting enzymes and mechanical movements consumes the prey. b. bacteriovorus invades the periplasm forming a bdelloplast, where it replicates by multiple fission. The factors involved in predation are the flagellum, mobilization, lytic enzymes, interaction genes "hit locus" bd0108 and bd0109, prey range, etc. The objective was to characterize phenotypic and molecular isolates of Bdellovibrio spp. in Mexico. Pathogenic bacteria of clinical interest were used as prey, and samples of water, soil, and animal feces, to isolate predatory bacteria, were confronted in order to observe lytic activity. Sequences of the 16S rRNA gene were used to amplify by PCR for the genus Bdellovibrio, sequences from the family Bdellovibrionaceae. Eightysix positive isolates for BALOs were obtained, cell lysis of the prey bacteria was observed, a prey range was performed, measuring the lytic activity (prey-predator).