Primary intraosseous oral squamous cell carcinoma (PIOSCC) is a rare malignant neoplasm that affects the jaws. Despite its aggressive biological behavior, there are no studies that evaluated the clinicopathological features of this tumor and parameters associated with its prognosis. The objective of the present study was to conduct a systematic review of the available data on oral and maxillofacial PIOSCC in order to determine its clinicopathological characteristics and biological behavior. We conducted a systematic review in May 2020 in multiple databases using a specific search strategy. Cases diagnosed as PIOSCC in the oral cavity and maxillofacial complex that had sufficient histopathological data, absence of ulceration in the oral mucosa, a negative result for a distant primary tumor, and radiographic evidence of an osteolytic lesion that was entirely or mostly surrounded by the jaw bones were included. A total of 109 published articles were included in our systematic review, corresponding to 257 cases. PIOSCC showed a male predilection (69.3%) and a preference for the mandible (7:1), with the posterior region being the most commonly affected site. The mean age at diagnosis was 57.3 years. Cortical expansion, pain, and lip/facial paresthesia were the most common clinical features. Regarding histopathological features, most PIOSCC were well-differentiated and the solid subtype was the most common. Statistical analysis showed that PIOSCC located in the mandible (p = 0.03) and recurrence (p < 0.01) were significantly associated with a higher mortality rate. PIOSCC has a poor prognosis, with high rates of mortality.

No abstract

As infecções sexualmente transmissíveis (ISTs) continuam sendo um desafio atual e preocupante para a saúde pública brasileira. Muitas dessas infecções podem acometer a cavidade oral, tornando assim a boca um meio de transmissão e de rastreamento. Por seu conhecimento técnico-cientifico, os dentistas estão em uma posição privilegiada para atuar nesse embate. O objetivo do estudo é compreender sobre a atuação do dentista da atenção primaria à saúde (APS) no Brasil na prevenção, diagnóstico, manejo, ações de promoção e educação em saúde voltados as ISTs e a saúde sexual por meio de uma revisão bibliográfica da literatura. Foi realizado uma busca utilizando descritores remetente ao assunto nas bases de dados Scielo, Web of Science, LILACS, PubMed, Scopus e Google Escolar, sendo incluídos aqueles estudos enquadrados nos critérios de inclusão. Todavia, nenhum estudo investigou o objetivo do presente estudo, sendo realizado sugestões de ações que o dentista pode realizar na atenção básica que contribuam no combate as ISTs por meio de informações contidas na literatura. Conclui-se que mais pesquisas devem ser realizadas nesse âmbito e que o dentista pode ter um papel de extrema importância no combate as ISTs na atenção básica.

The history of muscle biopsy dates back to 1860, when Duchenne first performed a biopsy on a patient with symptoms of myopathy (1) . Since then, the basic and clinical science of muscle and muscle disease has gone through three stages of development: the classical period, the modern stage and the molecular era.

Líquen plano oral: relato de caso com diferentes aspectos clínicos Liquen oral plan: case report with different clinical aspects