The use of machine learning and data mining algorithms in educational contexts has evolved due to the large availability of data generated mainly in virtual learning environments. This study makes a comparative analysis of five classifiers in the task of predicting students with risk of dropping out in undergraduate courses by distance education. The results showed a small advantage for the use of Logistic Regression in the data analyzed, with success rates above 90% in the predictive model. Resumo.O uso de algoritmos de mineração de dados e de aprendizagem de máquina em contextos educacionais tem evoluído em razão da grande disponibilidade de dados geradas principalmente em ambientes virtuais de aprendizagem. Este estudo faz uma análise comparativa de cinco classificadores na tarefa de predição de alunos com risco de evasão em cursos de graduação por EAD. Os resultados apontaram uma pequena vantagem para o uso da Regressão Logística nos dados analisados, com taxas de sucesso acima de 90% no modelo preditivo.

In the long history of mankind, animals have played significant roles.We owe much of our intellectual sophistication and societal status to animal husbandry. 1 Farming and agriculture have allowed humans to control their environment and an improved nutrition. The first rural settlements marked the birth of the ancient civilizations, 2 but also triggered the first zoonotic outbreaks and the beginning of public health concerns. 3 The earliest records of animal use coincide with the appearance of Hippocrates' concepts and the birth of Western medicine. 2 Jumping ahead 2400 years, in the year 2018 more than 20 000 animal subjects-exceeding 200 species-were part of translational studies worldwide, 4 in pre-clinical trials. 2 Animal modelling can provide reliable data to elucidate human diseases. 5 Despite benefiting our quality of life, animal research remains controversial. 3 There is a growing sense of disapproval over using household pets in experiments. 1 New technologies have been created to replace animals in research, but the position of ideal bone substitute remains open. 6 Thus, primary research on novel models continues paramount. 7 AbstractAnimal models are live subjects applied to translational research. They provide insights into human diseases and enhance biomedical knowledge. Livestock production has favored the pace of human social development over millennia. Today's society is more aware of animal welfare than past generations. The general public has marked objections to animal research and many species are falling into disuse. The search for an ideal methodology to replace animal use is on, but animal modeling still holds great importance to human health. Bone research, in particular, has unmet requirements that in vitro technologies cannot yet fully address. In that sense, standardizing novel models remains necessary and rabbits are gaining in popularity as potential bone models. Our aim here is to provide a broad overview of animal modeling and its ethical implications, followed by a narrower focus on bone research and the role rabbits are playing in the current scenario. K E Y W O R D Sanimal experimentation, bone density, Lagomorpha, translational medical research MACEDO Et Al.

Abstract. The use of Transactional Distance Theory constructs [Moore, 1973;1993;2013] as predictors of student dropout in distance education (DE) [Moore, 1973;1993;2013] Resumo. O uso dos construtos da Teoria da Distância Transacional IntroduçãoO desenvolvimento da Educação a Distância (EAD) tem sido apoiado por teorias que apoiam o planejamento e a execução de cursos mais eficientes. As pesquisas na área refletem o crescimento dessa modalidade, à medida que buscam atenuar problemas decorrentes dessa expansão, como os altos índices de evasão ainda verificados nesses cursos.Para a maioria das instituições que participou do Censo Anual da EAD no Brasil em 2015, o grande obstáculo enfrentado foi a evasão nos cursos, quando para 40% das instituições pesquisadas, a taxa média de evasão foi entre 26% e 50% nos cursos totalmente ofertados a distância.Partindo de uma necessidade da aplicação de teorias da EAD, no sentido de auxiliar no enfrentamento de um dos desafios da modalidade, esta pesquisa enfocou a Teoria da Distância Transacional, proposta por Moore (1973, 1993, 2013) como marco teórico principal do estudo,

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