Purpose -This paper aims to examine how e-learning can add value to a postgraduate distance learning course using a combination of media for teaching and learning in the field of nutrition and HIV and AIDS. Design/methodology/approach -Data were gathered through the survey method using questionnaires, group discussions and interviews. Descriptive quantitative statistics supported by qualitative techniques were used to gather data. Findings -Findings from this research indicate that implementing e-learning as a mode of teaching and learning (provided that it is properly implemented and presented) can add value to an outcomes-based, distance learning course. E-learning provides: support for a paper-based, distance learning course in nutrition and HIV and AIDS; students with access to information and knowledge about the basic concepts of nutrition and HIV and AIDS; an alternative and interactive learning experience while encouraging self-directed explorative knowledge formation; and a means to develop critical thinking skills and methods of communication needed for independent, lifelong learning. Practical implications -The selected instructional media can be applied successfully to adult and distance learning in the field of HIV and AIDS as well as nutrition. Originality/value -The paper shares findings on the integration of e-learning into a HIV and AIDS nutrition course (for non-medical students), offered in an African context through open distance learning and demonstrates how the course addresses student profile and limited resources.