Objective: Endometriosis is the growth of functional endometrial gland and stroma outside the uterine cavity. Scar endometriosis is a very rare disease and is diagnosed by histopathologic examination. Endometriosis may be detected in the scar tissue after a previous gynecological operation. Scar endometriosis is a mass consisting of endometrial glands and stroma that may develop in the incision scar tissue or in the neighborhood after gynecologic procedures performed especially by cesarean section. We aimed to present the patients who had a history of gynecologic surgery, who presented with mass and/or pain complaints especially in the corner regions of the previous incision line, and underwent surgical excision and reported as endometriosis as a result of postoperative pathology. Materials and Methods: Patients who presented to the general surgery outpatient clinic between September 2018 and December 2019 with complaints of palpable mass, pain and swelling at the edge of the pfannenstiel incision were evaluated. The records of patients who underwent surgery with a preliminary diagnosis of endometriosis and reported as endometriosis as a result of pathology were reviewed retrospectively. Results: Surgical excision was performed in 14 patients with a preliminary diagnosis of endometriosis. The mean age of the patients was 29.5 (min: 18-max: 39 years). All patients had a history of cesarean section as a history of abdominal surgery. When the pathology results were examined, all the reports were endometriosis externa. In the pathology reports, the mean diameter of the lesion was 25x20x17mm (min: 10- max: 40). Result: Endometriosis should be considered in patients with a history of palpable mass and pain around the incision site in patients with a history of gynecologic surgery.
Background GATA binding protein 3 (GATA-3) is one of the six transcription factor family members and is important for glandular development in the breast. Its expression becomes important in breast cancer. We aimed to compare GATA-3 immunoreactivity and pathological prognostic factors in patients with invasive ductal carcinoma. Material and Methods Our study was conducted retrospectively with 300 breast invasive ductal carcinoma patients who were operated on in our hospital between May 2013 and June 2014. Patient reports, slides and blocks in the pathology archive were scanned. GATA-3 immunohistochemical (IHC) staining was evaluated according to the nuclear staining, intensity and percentage. The relationship between clinicopathological prognostic parameters and GATA-3 IHC staining results was investigated. Results A positive staining was observed in 286 (95.3%) cases. According to the GATA-3 staining intensity and percentage, 210 (70%) cases stained strongly and 246 (82%) stained +4, respectively. There was a significant relationship between GATA-3 immunoreactivity with ER, PR, Cerb-B2, Ki-67, mitotic degree, mitotic count and histological grade. Conclusions There was a correlation between the high expression of GATA-3 and good prognostic markers. Hormone receptors can be evaluated with Cerb-B2 and Ki-67 and used as prognosis determinants in breast cancers. They can be used to identify both primary and secondary breast tumors.
Splenik hamartom (Splenoma) normal dalak elemanlarının anormal yerleşimiyle karakterize dalağın nadir benign malformasyonudur. Genellikle asemptomatiktir. Otopsilerde ya da splenektomilerde insidental olarak saptanır. Nadiren trombositopeni, splenomegali ve anemi gibi semptomlar oluşturabilir.
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