We present a non-relativistic theory of quantum radiation generated by shaking a two-level atom in vacuum. Such radiation has the same origin of photon emission in dynamical Casimir effect. By performing a time-dependent "dressing" transformation to the Hamiltonian, we derive an interaction term that governs the radiation. In particular, we show that photon pairs can be generated, not only by shaking the position of the atom, but also by changing the internal states of the atom. As applications of our theory, we calculate the emission rate from an oscillating atom, and the multi-photon state generated in a single-photon scattering process.

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