Background: Cell-assisted lipotransfer (CAL) has been proposed to be beneficial for improving graft retention. Clinically, CAL involves the isolation of the stromal vascular fraction (SVF) from a portion of the lipoaspirate at the time of surgery. However, most studies related to SVF breast augmentation lacked a rigorous methodology and well-designed control. Objective: We aimed to determine the potential improvement of SVF enrichment in fat grafting for breast augmentation with objective volume assessment. Methods: From April 2015 to January 2016, 169 patients were enrolled after applying the exclusion criteria. Among them, 97 patients who underwent conventional fat grafting for breast augmentation were assigned to group A. The other 72 patients underwent SVFenriched fat grafting for breast augmentation and were assigned to group B. A retrospective comparative study was conducted to evaluate the graft survival using 3-dimensional laser scanning. Results: There was no significant difference between the 2 groups in terms of mean age, original breast volume, grafted fat volume, and postoperative weight change. Breast volume assessments revealed that the percentage of graft survival at 12 months was 69.2% in group A and 71.1% in group B, with no significant difference (p=0.641). The preoperative body mass index was significantly lower in group A than in group B. The volume of suctioned fat was significantly less in group A. The operation time was significantly shorter in group A. The postoperative complication rates were significantly lower in group A than in group B. Conclusion: SVF-enriched fat grafting for breast augmentation was associated with a larger amount of harvested fat, a longer operation time, and a higher incidence of complications. The graft retention rate was not significantly increased. The findings of our study do not support the use of SVF in fat grafting for breast augmentation.
Background:The Timed Up and Go (TUG) test is commonly used to assess motor function and gait stability in the elderly, including patients with chronic kidney disease (CKD). Furthermore, the handgrip strength test is used to evaluate general muscle strength and may help identify weakness, a key element of frailty.Objectives:This study aimed to determine whether the handgrip strength test is a suitable screening tool before the TUG test because it requires less physical effort and likelihood of adverse events associated with falling during testing.Methods:A total of 120 patients with CKD on hemodialysis participated in the study. The associations or correlations among handgrip strength, TUG test, and routine nutritional biomarkers were analyzed.Results:A significant correlation was observed between handgrip strength and TUG test in all patients (R= −0.39,P= 1*10-5), even in patients with diabetic kidney disease (n= 56,R= −0.36,P= 0.0065). Interestingly, when dividing the patients into two groups according to hemoglobin A1c (HbA1c) levels (<7% vs. ≥7%), no significant differences in handgrip strength or completion time of the TUG test were observed between both groups.Conclusion:In patients on hemodialysis with decreased mobility, measuring grip strength can be a reliable marker as an initial screening to determine whether patients can exert the necessary physical effort to perform the TUG test. Furthermore, a HbA1c <7% did not provide additional benefits in terms of muscle strength and mobility to patients with diabetes on hemodialysis.
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