Background SARS-CoV-2 is frequently shed in the stool of patients hospitalised with COVID-19. The extent of faecal shedding of SARS-CoV-2 among individuals in the community, and its potential to contribute to spread of disease, is unknown. Methods In this prospective, observational cohort study among households in Liverpool, UK, participants underwent weekly nasal/throat swabbing to detect SARS-CoV-2 virus, over a 12-week period from enrolment starting July 2020. Participants that tested positive for SARS-CoV-2 were asked to provide a stool sample three and 14 days later. In addition, in October and November 2020, during a period of high community transmission, stool sampling was undertaken to determine the prevalence of SARS-CoV-2 faecal shedding among all study participants. SARS-CoV-2 RNA was detected using Real-Time PCR. Results A total of 434 participants from 176 households were enrolled. Eighteen participants (4.2%: 95% confidence interval [CI] 2.5–6.5%) tested positive for SARS-CoV-2 virus on nasal/throat swabs and of these, 3/17 (18%: 95% CI 4–43%) had SARS-CoV-2 detected in stool. Two of three participants demonstrated ongoing faecal shedding of SARS-CoV-2, without gastrointestinal symptoms, after testing negative for SARS-CoV-2 in respiratory samples. Among 165/434 participants without SARS-CoV-2 infection and who took part in the prevalence study, none had SARS-CoV-2 in stool. There was no demonstrable household transmission of SARS-CoV-2 among households containing a participant with faecal shedding. Conclusions Faecal shedding of SARS-CoV-2 occurred among community participants with confirmed SARS-CoV-2 infection. However, during a period of high community transmission, faecal shedding of SARS-CoV-2 was not detected among participants without SARS-CoV-2 infection. It is unlikely that the faecal-oral route plays a significant role in household and community transmission of SARS-CoV-2.
Waves propagating near an event horizon display interesting features including logarithmic phase singularities and caustics. We consider an acoustic horizon in a flowing Bose-Einstein condensate where the elementary excitations obey the Bogoliubov dispersion relation. In the hamiltonian ray theory the solutions undergo a broken pitchfork bifurcation near the horizon and one might therefore expect the associated wave structure to be given by a Pearcey function, this being the universal wave function that dresses catastrophes with two control parameters. However, the wave function is in fact an Airy-type function supplemented by a logarithmic phase term, a novel type of wave catastrophe. Similar wave functions arise in aeroacoustic flows from jet engines, path integrals in radio astronomy, and also gravitational horizons if dispersion which violates Lorentz symmetry in the UV is included. The approach we take differs from most previous authors in that we analyze the behaviour of the integral representation of the wave function using exponential coordinates. This allows for a different treatment of the branch cuts and gives rise to an analysis based purely on saddlepoint expansions. We are thereby able to resolve the multiple real and complex waves that interact at the horizon and its companion caustic. We find that the horizon is a physical manifestation of a Stokes surface, marking the place where a wave is born, and that the horizon and the caustic do not in general coincide: the finite spatial region between them delineates a broadened horizon.
No abstract
No abstract
No abstract
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.