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LToI. 7:: @-carbon of serine underwent approximately the same dilution.The methyl group of the thymine, isolated in experiment 1, had an activity of 7360 c . p m 3 and 0.0126 atom D. This would indicate a dilution of 43 for the carbon and 57 for the D.A contribution of D to the methyl groups from the ar position of serine (via a-deuterioglycine6), which would significantly change these ratios, is unlikely, since glycine is a poor source of methyl group^,^*^ and the a-hydrogen atoms of glycine' and (1) This method was conceived prior to 1946 as an alternative to the approach of Johnson, Jones and Schneider (ref. 2); see also the M.S. thesis of W. P. Schneider, University of Wisconsin, 1946. A similar approach has been suggested independently by