No abstract

Background: Hepatocellular carcinoma (HCC) has become the third leading cause of cancer-related death worldwide, and its incidence rate is increasing. Magnetic resonance elastography (MRE) can indirectly realize the accurate non-invasive evaluation of liver reserve function in HCC patients. In this study, we aimed to evaluate the effectiveness of MRE in the diagnosis of HCC patients.Methods: We searched globally-recognized electronic databases, such as PubMed, EMBASE, China National Knowledge Infrastructure, and Cochrane Central, for relevant literature on MRE prediction of HCC. The diagnostic performance of all studies was quantitatively summarized using a bivariate random effects model including heterogeneity analysis, receiver operating characteristic (ROC) curve, and bias determination.Results: The diagnostic accuracy of MRE for HCC was based on 1,735 patients. The sensitivity (31-100%) was lower than the specificity (81-94%). The overall sensitivity was 64% [95% confidence interval (CI): 46-79%; I 2 =92.44%], and the overall specificity was 85% (95% CI: 82-88%; I 2 =67.86%). Limited publication bias was observed in this study, and the sensitivity analysis showed that the study was robust. Discussion:The results of our meta-analysis show that MRE has moderate sensitivity and excellent specificity in the detection of HCC. MRE can be an effective diagnostic tool for HCC and can provide strong support for the selection of clinical treatment methods and prognostic judgment.

Objective: To study and compare the clinical effects of the combination of different interventional embolization chemotherapy and radiofrequency ablation in patients with primary liver cancer. Methods: In this paper, based on the target data validation of those 60 patients with primary liver cancer treated in the hospital during the period from May 2017 to May 2018, the double-blind method was used for the comparison between groups. Patients in the reference group were treated with the combination of cis-platinum interventional chemoembolization regimen and radiofrequency ablation, while those in the experimental group were treated with the combination of lobaplatin interventional chemoembolization regimen and radiofrequency ablation. Then, the efficacy of both groups was compared. Results: After the treatment, the clinically effective total value, the calculation value of adverse reactions, and the value of IgA, IgM, IgG and AFP of the experimental group were compared with those of the reference group. In addition, the value of IgA, IgM, IgG and AFP of both groups after and before the treatment were compared. The experimental results showed that the data was statistically significant (P<0.05). Conclusion: The combination of lobaplatin and cisplatin interventional embolization chemotherapy and radiofrequency ablation has some effects in patients with primary liver cancer, but the former one showed more significant effects.

Urban parks play a distinctive and important role in satisfying residents’ demands on leisure and recreation, and thus have become the focus of research in the field of urban planning and sustainable development. This paper used equity as indicator to combine both the supply and demand sides of urban park service. Taking Xiamen as the study case, the relationship between spatial distribution of population and park services was analyzed. The results show that while population density has a significant spatial relationship with urban park service level at the city scale, Xiamen has the problem of neglecting the equity of urban park service between people and regions within the city. The proposed approach builds up the linkage between urban park service and urban population in order to evaluate the performance of urban park. Although the mechanism remains to be discussed, this study provides a useful auxiliary tool for constructing a guideline for urban green space planning, since urban park is increasingly seen as a kind of restricted public resource and ensuring its equity should be an important task for city mangers.

Objective: To analyze the application value of MRI and CT diagnosis for those with lumbar disc herniation. Methods: The data of 62 patients with LDH treated in our hospital from January 2019 to December 2019 were analyzed retrospectively. All patients were diagnosed as LDH after operation, and 62 patients were treated with MRI and CT. The accuracy of CT and MRI in the diagnosis was analyzed according to the gold standard of operation results. Results: 62 patients were diagnosed as LDH after operation, including 25 cases with intervertebral disc herniation, 12 cases with intervertebral disc prolapse, 8 cases with intervertebral disc nodule, 7 cases with intervertebral disc dissociation as well as 10 cases with intervertebral disc bulge. The accuracy of MRI diagnosis (95.16%) was higher than that of CT (75.81%), and the difference was statistically significant (P<0.05). Conclusion: For the diagnosis of LDH, MRI is more accurate, but CT is faster and cheaper. Both of them have their own advantages and can be chosen clinically according to the actual situation of patients on the basis of ensuring the diagnostic accuracy.