This paper documents an unusual example of hypoplastic anemia, intermittent hemoglobinuria appearing in cold weather, and lymphoproliferative disease associated with hypogammaglobulinemia and repeated infections, followed by the appearance of a monoclonal gammopathy (IgG-Kappa) and Bence Jones proteinuria (Kappa), with tissue lesions more characteristic of macroglobulinemia than of multiple myeloma, in a middle-aged Negro.
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