This is an exploratory, descriptive, prospective study, with a quantitative and qualitative approach. The aims were: to identify the perception of managers of University Hospitals in the city of São Paulo, in relation to the factors that are producing new trends in people management and what changes these provoke in the people management models; to identify the focus of attention and the difficulties regarding the management of policies for managing people, through the trends in the macro context, and to map the gaps between the trends identified, foci of attention and difficulties, and the competences required for managers who work in the management context of university hospitals; to formulate proposals in which the development of managers of people in the health field is aligned to the new demands of the next decade. The study had three UHs as the scenario and counted on the participation of the strategic level. To achieve the formulated aims, the Delphi technique was employed, in order to better comprehend the current situation and the trends in people management in university hospitals. The results showed that People Management will suffer significant changes in the next 10 years (86.7%) which should focus predominantly on practices and management instruments (50%). The Trends of Change in the Environment considered high impact and that can affect decisions on strategies and policies for managing people of the UHs were: the search for the quality of the processes and products, questioning the social role of the institutions, citizenship and consumer rights, and changes in technology applied to the production and organizational processes in the UHs. Regarding the Principles that will Guide the People Management Models, five principles were considered highly relevant: empowerment, HR management consistent with the business of the organization, commitment of the workforce with the organizational objectives, corporate education and self-development. It was observed that these principles had been partially introduced and will have to be the main focus of attention of the managers for next the 10 years. Regarding the People Management Policies, of the 13 management policies considered most relevant for the future, the managers indicated: proportionately less benefits in the remuneration (mean 7.9), flexible benefits defined by the participation of the employees (mean 7.8) and greater power of decision of the directors regarding the remuneration of their staff (mean 7.5) as having a high degree of difficulty in implementing these People Management policies of the UHs. In relation to the Format of the HR Function in the UHs, three trends were considered excellent and that they will be taken into consideration in the decisions regarding people management: the decisions will go to the manager of the unit (93.3%), migration of corporative people management roles to the units (93.3%) and the primary role of the area will be to provide new processes and knowledge for the internal clients (93.3%). The results indicate tha...