In this paper, a modified conjugate gradient (MCG) algorithm is proposed for solving the force reconstruction problems in practical engineering. This new method is derived from a stable regularization operator and is also strictly proved using the mathematical theory. Moreover, we also prove the sufficient descent and global convergence characteristic of the newly developed algorithm. Finally, the proposed algorithm is applied to force reconstruction for the airfoil structure and composite laminated cylindrical shell. Numerical simulations show that the proposed method is highly efficient and has robust convergence performances. Additionally, the accuracy of the proposed algorithm in identifying the expected loads is satisfactory and acceptable in practical engineering.

Abstract:Objective: Myostatin has recently been proposed as an important factor that not only regulates skeletal muscle mass, but also body fat mass. The aim of our study is to explore serum myostatin levels in overweight patients and its association with metabolic-related characteristics.Methods: 40 overweight patients and 40 normal weight controls were recruited, and serum myostatin were measured by ELISA methods and the relationships between myostatin and metabolic-related parameters were investigated. Conclusion: Serum myostatin levels in overweight patients are notably increased and positively correlated with BMI, body weight, waist and hip circumference, TNF-, suggesting myostatin is a metabolic regulatory factor.