dMolecular diagnostic tools have been used increasingly in the characterization of the transmission of cryptosporidiosis and microsporidiosis in developing countries. However, few studies have examined the distribution of Cryptosporidium species and Enterocytozoon bieneusi genotypes in AIDS patients receiving antiretroviral therapy. In the present study, 683 HIV-positive patients in the National Free Antiretroviral Therapy Program in China and 683 matched HIV-negative controls were enrolled. Cryptosporidium species and subtypes and Enterocytozoon bieneusi genotypes were detected and differentiated by PCR and DNA sequencing. The infection rates were 1.5% and 0.15% for Cryptosporidium and 5.7% and 4.2% for E. bieneusi in HIV-positive and HIV-negative participants, respectively. The majority (8/11) of Cryptosporidium cases were infections by zoonotic species, including Cryptosporidium meleagridis (5), Cryptosporidium parvum (2), and Cryptosporidium suis (1). Prevalent E. bieneusi genotypes detected, including EbpC (39), D (12), and type IV (7), were also potentially zoonotic. The common occurrence of EbpC was a feature of E. bieneusi transmission not seen in other areas. Contact with animals was a risk factor for both cryptosporidiosis and microsporidiosis. The results suggest that zoonotic transmission was significant in the epidemiology of both diseases in rural AIDS patients in China.

There is profound interest in knowing the degree to which China's institutions are capable of protecting its natural forests and biodiversity in the face of economic and political change. China's 2 most important forest-protection policies are its National Forest Protection Program (NFPP) and its nationallevel nature reserves (NNRs

China is credited with undertaking some of the world's most ambitious policies to protect and restore forests, which could serve as a role model for other countries. However, the actual environmental consequences of these policies are poorly known. Here, we combine remote-sensing analysis with household interviews to assess the nature and drivers of land-cover change in southwestern China between 2000-2015, after China's major forest protection and reforestation policies came into effect. We found that while the region's gross tree cover grew by 32%, this increase was entirely due to the conversion of croplands to tree plantations, particularly monocultures. Native forests, in turn, suffered a net loss of 6.6%. Thus, instead of truly recovering forested landscapes and generating concomitant environmental benefits, the region's apparent forest recovery has effectively displaced native forests, including those that could have naturally regenerated on land freed up from agriculture. The pursuit of profit from agricultural or forestry production along with governmental encouragement and mobilization for certain land usesincluding tree planting-were the dominant drivers of the observed land-cover change. An additional driver was the desire of many households to conform with the land-use decisions of their neighbors. We also found that households' lack of labor or financial resources, rather than any policy safeguards, was the primary constraint on further conversion of native forests. We conclude that to achieve genuine forest recovery along with the resulting environmental benefits, China's policies must more strongly protect existing native forests and facilitate native forest restoration. Natural regeneration, which thus far has been grossly neglected in China's forest policies, should be recognized as a legitimate means of forest restoration. In addition, social factors operating at the household level, notably the pursuit of profit and conformation to social norms, should be harnessed to promote better land-cover, biodiversity, and environmental outcomes. More generally, for China and other countries to succeed in recovering forests, policies must clearly distinguish between native forests and tree plantations.