Introduction and objectives: autism spectrum disorder (ASD) is a neurodevelopmental disorder, which exhibits symptoms such as early-onset impairment of interaction and social communication, as well as repetitive and restricted sensory and motor behavior. This study aims to carry out a systematic review regarding the application of intervention strategies for behavior management in autism spectrum disorder in childhood and adolescence. Methods: A systematic search of Randomized Controlled Clinical Trials conducted between January 2016 and June 2021 found in PubMed, Scient direct y Scopus was performed. Keywords used were “Psychomotor, disorder, autism, behavior, intervention”, using with five search criteria, through corresponding Boolean operators “OR” and “AND” and source-specific search filters. Results: 2 845 records were found and, after further analysis, 45 articles were obtained for the final analysis, with a number of participants (n=3 439), age range: 8-17 years of age, confirmed diagnosis of autism spectrum disorder, with a profile in levels of severity, which ranged from those with greater involvement to those with highest functionality. Conclusions: The analysis of the studies included in this systematic review, allow to conclude that there are several strategies used in behavior management in autism spectrum disorder that contribute to reduce symptoms in this disorder. Keywords: Psychomotor, disorder, autism, behavior, intervention.