Patient: Male, 66-year-old Final Diagnosis: Guillain-Barré syndrome Symptoms: Paresthesia • weakness Medication: — Clinical Procedure: — Specialty: Immunology • Infectious Diseases • Neurology • Rehabilitation Objective: Unknown etiology Background: Since December 2020, multiple vaccines have mobilized mass immunization campaigns capable of mitigating the current SARS-COV-2 pandemic. Ad26.COV2.S (Johnson & Johnson/Janssen) is a recombinant, replication-incompetent vector vaccine encoding the SARS-CoV-2 spike (s) protein and is especially protective against severe-critical disease. It is a single-dose injection; adverse effects after vaccine administration are usually mild and self-limited, including pain at the injection site, headache, fatigue, muscle aches, and nausea. Severe adverse events involving hospitalization and death after Ad26.COV2.S rarely occur. However, not unlike previous viral vector vaccines, ongoing clinical trials may unveil rare complications of Ad26.COV2.S. Guillain-Barré syndrome (GBS) is an autoimmune demyelinating polyneuropathy that can potentially manifest severe neurological symptoms after vaccination. Case Report: This report describes a case of classic GBS features that manifested 14 days after a single Ad26.COV2.S vaccine injection. The patient developed flaccid paralysis with treatment-related fluctuations. Our findings warrant further investigation into the potential relationship between SARS-CoV-2 vaccinations and the development of GBS. Conclusions: A temporal association between the Ad26.COV2.S (Johnson & Johnson/Janssen) vaccine and the onset of GBS was demonstrated in this case report. A feasible underlying pathogenic mechanism involves the cross-reactivity of antibodies stimulated by adenovirus vaccine components and peripheral nerve glycoproteins. However, there is currently insufficient evidence to support a causal relationship between Ad26.COV2.S and the development of GBS. Further evidence gathered from clinician surveillance and clinical trials are needed to draw these conclusions.
El articulo discute la formación territorial como teoría y como método para analizar la formación/transformación de territorios en zonas de frontera. Propone la formación del territorio en las fronteras como un proceso en el cual hay continuidades, discontinuidades, rupturas, flujos y contraflujos; como resultado de las relaciones conflictivas entre múltiples territorialidades por la apropiación material y simbólica de un mismo espacio; que requiere ser analizada en un caso concreto, con un contexto social y geográfico preciso; y que articula las variables espacio-tiempo. Se argumenta que hay una superposición de territorialidades, que no es sólo un proceso contemporáneo, es un proceso histórico, de larga duración, que se revela en la conflictividad permanente entre esas diferentes territorialidades que se encuentran en las fronteras, en una la lucha para mantener sus procesos de territorialización y reterritorialización.
El artículo tiene por objetivo determinar las variables que pueden condicionar la decisión observable de un individuo con respecto a escuchar música grabada en Colombia. Para ello, se estiman modelos probit usando microdatos de la Encuesta de Consumo Cultural 2008. Los resultados muestran que individuos con educación superior, que toman cursos y talleres culturales y se sitúan en los niveles medios y altos de estrato socio-económico presentan la mayor probabilidad de escuchar música grabada. Igualmente, se encuentra que individuos que se auto-reconocen como afro-descendientes se asocian con una menor probabilidad de escuchar música grabada. El artículo contribuye a la escasa literatura empírica sobre los determinantes de la participación cultural en países de América Latina.
This paper describes the process of incorporating a virtual environment for the practice of the coordination skill to the Web Environment for Surgical Skills in Training in Otolaryngology, WESST -OT. Additionally, a complementary module which allows session customization and the inclusion of anomalies and pathologies in the paranasal region is presented.
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