In much of the developed world, hospitals are the second and final tier of care, with the majority of medical care taking place in community-based ambulatory settings. The involvement of psychologists in hospital practice varies across nations, but where it exists, their activities are remarkably similar. The organization of national health care systems and payment for health care also vary greatly across nations, and those differences likely influence the activities of psychologists in those hospitals.In this chapter, I review the definition of general hospitals, summarize the extant data on the number of psychologists working there, and outline the different professional activities of psychologists in those settings. The chapter concludes by identifying the unique contributions of the hospital setting and by anticipating future opportunities there for clinical psychologists.