Gastric cancer (GC) is the second leading cause of cancer mortality and remains the fourth common cancer worldwide. The effective and feasible methods for predicting the possible outcomes for GC patients are still lacking. While genetic profiling might be suitable in some way, the application of gene expression signatures has been show to be a robust tool. Here, by performing a comprehensive search in PubMed, we provided an up-to-date summary of 39 prognostic gene signatures for GC patients, and described the processing procedure of the selection, calculation and construction of gene signature. We also reviewed current web tools including PROGgene and SurvExpress that can be used to analyze the prognostic value of multiple genes for GC. This review will aid in comprehensive understanding of the current prognostic gene signatures to accurately predict the outcome of GC patients, and may guide the future clinical management when the reliability of these signatures is validated in clinics.

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Artificial Intelligence significantly promotes humans' production efficiency and facilitates our daily life. Meanwhile, the climate of people's employment is also under great impact. Through a group interview with six scholars and designers from the fields of Architecture, Urban Planning, Landscape Architecture, and Industrial Design, Landscape Architecture Frontiers attempts to provoke public attention on the challenges and opportunities (would be) brought by Artificial Intelligence by asking three questions: What is Artificial Intelligence? How would it influence designers' working process and final results? And, what lifestyles would we have in the future under the influence of Artificial Intelligence? Most interviewees agree that, though Artificial Intelligence has largely helped us lessen workload on repetitive or routine tasks, nowadays it can neither be intelligent enough to have selfconsciousness or perform creative jobs, nor offer ethical solutions or value judgments, because it is operated under weighted computing which is programmed by the majority rule. However, all the interviewees believe that Artificial Intelligence will make a big change on people's future lifestyles, far beyond our imagination.

analyzed the data. Tieshan Teng, Qiming Li, and Longxiang Xie drafted the manuscript.