An exploratory descriptive study of donor families and recipients of cadaveric organs was done to determine their feelings about direct contact with each other. Direct contact was desired by 70% of donor families and 75% of recipients. Donor families wanted to see firsthand the benefit of the transplant to another person. Recipients primarily wanted to express gratitude. Both groups think they have a right to meet. Although both think these interactions should be professionally regulated and facilitated, they do not think the transplant center or the organ procurement organization is responsible for the outcome of a meeting. Donor families and recipients think the process should be gradual with prior correspondence. On the basis of our findings, we have developed a list of suggested guidelines to use when facilitating an interaction.

Most respondents (84%) indicated that family support was the most helpful thing in dealing with their grief, followed by the support of friends (74%) and religious and cultural beliefs (37%). Most (75%) indicated that they agreed to donation so that something positive could result from their loss. Most respondents (93%) felt that they were given enough information to make an informed decision about donation, and 6% indicated that the donation process interfered with funeral or memorial arrangements. More than 95% understood that their loved one had died before they were approached for consent. Consistent with previous studies, 12% said they still had unanswered questions about aspects of donation, and 15% of respondents indicated that the discussion about organ donation added more emotional stress to their overall experience.

An exploratory descriptive study of donor families and recipients of cadaveric organs was done to determine their feelings about direct contact with each other. Direct contact was desired by 70% of donor families and 75% of recipients. Donor families wanted to see firsthand the benefit of the transplant to another person. Recipients primarily wanted to express gratitude. Both groups think they have a right to meet. Although both think these interactions should be professionally regulated and facilitated, they do not think the transplant center or the organ procurement organization is responsible for the outcome of a meeting. Donor families and recipients think the process should be gradual with prior correspondence. On the basis of our findings, we have developed a list of suggested guidelines to use when facilitating an interaction.

Most respondents (84%) indicated that family support was the most helpful thing in dealing with their grief, followed by the support of friends (74%) and religious and cultural beliefs (37%). Most (75%) indicated that they agreed to donation so that something positive could result from their loss. Most respondents (93%) felt that they were given enough information to make an informed decision about donation, and 6% indicated that the donation process interfered with funeral or memorial arrangements. More than 95% understood that their loved one had died before they were approached for consent. Consistent with previous studies, 12% said they still had unanswered questions about aspects of donation, and 15% of respondents indicated that the discussion about organ donation added more emotional stress to their overall experience.

research into preservation methods that target molecular mechanisms of organ injury is being actively pursued.Newer preservation methods, including targeted perfusion solutions and advanced machine perfusion methods may provide opportunities to treat, maintain, and assess marginal organs and ultimately improve transplant outcomes. This review summarizes recent advancements in preservation solutions and machine perfusion methods, including hypothermic, normothermic, and subnormotherimic machine perfusion applicable to kidney, liver, pancreas, intestine, heart, and lung transplantation. MethodsThe comprehensive review of the literature was performed by systematic analysis of published literature to February, 2019. The PubMed database (https:// www.ncbi.nlm.nih.gov/pubmed/) was searched for variations of keywords: hypothermic machine reperfusion; normothermic machine reperfusion; subnormothermic machine reperfusion; kidney transplant perfusion; liver transplant perfusion; pancreas transplant perfusion; intestine transplant perfusion; heart transplant perfusion; lung transplant perfusion; and perfusion solution additions. Publication review included deceased and live donor types, cellular, animal and human studies. Prospective and retrospective clinical studies including center studies, meta-analyses and review articles were included. Waitlist and transplantation data was included from the Organ Procurement and Transplantation Network (OPTN; https://optn.transplant.hrsa.gov/data/organ-datasource/).