In the search for new molecules capable of treating intestinal parasitosis with less risk in the short, medium and long term, the potential of medicinal plants is explored. Psidium guajava is plant used traditional medicine to treat gastrointestinal disorders and intestinal parasitosis. According to the synthesis of reviews presented here, very few studies have been devoted to the evaluation of anthelmintic activities of Psidium guajava. Psidium guajava has secondary metabolisms responsible for its demonstrated biological activities and reported medicinal uses. The leaves and fruits of Psidium guajava contain essential oils that know a great variation in the content of compounds. Geographic and edaphic conditions, and genetic factors are factors that influence the composition of essential oils. The direct consequence is the observation of several chemotypes of essential oils of Psidium guajava. Further studies are important to demonstrate the efficacy of Psidium guajava in the treatment of intestinal parasitosis.

The essential oils from Ocimum gratissimum, Hyptis suaveolens (Lamiceae) and Psidium guajava (Myrtaceae) have biological properties. The aim of this work is to compare the effect of essential oils of these three medicinal plants on weight growth, hematological and biochemical parameters of treated rats through the procedure of acute toxicity evaluation on Wistar rats. The doses applied are 100, 250 and 500mg/Kg bw for each of the essential oils From the results obtained, the effects of essential oils of Ocimum gratissimum, Hyptis suaveolens and Psidium guajava leaves on biochemical, hematological parameters and weight growth of rats are dose dependent. At the dose of 500mg/Kg bw, they significantly increased the rate of white blood cells, urea, creatinemia, transaminases and reduced the weight growth of rats by more than 10% (p<0.05) compared to the control lot. This shows that these essential oils can have toxic effects when applied in high doses.

This article aims to present the current state of the fight against gastrointestinal parasites in small ruminants from Improved Traditional Drugs (DTI). A host of scientific documents were consulted by means of search engines to gather the information useful for this synthesis. The failure of conventional treatments has led to the use of new methods to treat digestive pathologies due to internal parasitism in herds of sheep and goats. These include, among others, herbal medicine, homeopathy, aromatherapy, the mixed grazing system for small and large ruminants, ... All plant parts of plants can be used in the preparation of remedies. Several scientific studies show that plants are full of chemical compounds that cause anthelmintic effects on gastrointestinal parasites in small ruminants. Literature searches have revealed that studies on DTIs in the management of gastrointestinal nematodes in small ruminants are non-existent. In addition to the forms (decocted, macerated, infused, etc.) traditionally used by breeders, there are other forms that can be used to make DTIs from plant extracts. There are capsules, capsules, tablets etc. The placing on the market of DTIs requires official authorization based on the safety and reproducibility of the products. From the documents consulted, it appears that scientific research has not yet focused on the formulation of DTIs for the treatment of gastrointestinal parasitic nematodes in small ruminants. It will be useful to manufacture them to facilitate access to veterinary care and the sustainable management of animal health. Keywords: Improved Traditional Drugs; Gastrointestinal nematodes; Small ruminants, West Africa; Central Africa.

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