Wearing face masks during the Covid-19 pandemic has undeniable benefits from our health perspective. However, the interpersonal costs on social interactions may have been underappreciated. Because masks obscure critical facial regions signaling approach/avoidance intent and social trust, this implies that facial inference of approachability and trustworthiness may be severely discounted. Here, in our eyetracking experiment, we show that people judged masked faces as less approachable and trustworthy. Further analyses showed that the attention directed towards the eye region relative to the mouth region mediated the effect on approachability, but not on trustworthiness. This is because for masked faces, with the mouth region obscured, visual attention is then automatically diverted away from the mouth and towards the eye region, which is an undiagnostic cue for judging a target’s approachability. Together, these findings support that mask-wearing inhibits the critical facial cues needed for social judgements.