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The methodology for studying a tyre blow-out process using both experiments and simulations is presented in this paper. To achieve this, a tyre blow-out generator and an experimental device for tyre blow-out are developed. Moreover, tyre blow-out experiments in the static state are implemented. Then, the finite element tyre model corresponding to the experiments is established. The experimental results show that the tyre blow-out generator developed can effectively replicate the sudden inflation pressure loss without inflicting permanent damage on the tyre structure. The comparison between the simulations and the experiments shows that the finite element tyre model developed can simulate the tyre blow-out phenomenon and that the simulation analysis method is correct and effective. The tyre blowout generator developed and the finite element tyre model established therefore provide the basis for further simulations and investigations of tyre blow-out during the normal motion of a vehicle and its effect on the handling stability.