Taking cold-chain logistics as the research background and combining with the overall optimisation of logistics distribution networks, we develop two-stage distribution location-routing model with the minimum total cost as the objective function and varying vehicle capacity in different delivery stages. A hybrid genetic algorithm is designed based on coupling and collaboration of the two-stage routing and transfer stations. The validity and feasibility of the model and algorithm are verified by conducting a randomly generated test. The optimal solutions for different objective functions of two-stage distribution location-routing are compared and analysed. Results turn out that for different distribution objectives, different distribution schemes should be employed. Finally, we compare the two-stage distribution location-routing to single-stage vehicle routing problems. It is found that a two-stage distribution location-routing system is feasible and effective for the cold-chain logistics network, and can decrease distribution cost for cold-chain logistics enterprises.

Customer demand is dynamic and changeable; thus, optimality of the enterprise’s initial location cannot be guaranteed throughout the planning period in order to minimize site selection cost and maximize service reliability in the whole operation cycle. The enterprise planning period is divided into different stages, and a static location model is established at the fixed stage. In addition, a multi-stage dynamic location model is established by introducing the transfer cost between adjacent stages. To reduce the difficulty of solving the dynamic location model, first, we determined the optimal site selection and allocation strategy for each stage. Second, we designed a novel method that transforms the multi-stage dynamic location problem into the shortest path problem in graph theory. Finally, the Dijkstra algorithm was used to find the optimal dynamic location sequence so that its cumulative cost was the lowest in the whole planning period. Through a case study in China, we compare the costs of static and dynamic locations and the location cost under different objectives. The results show that this dynamic location generates more income (as it reduces cost) in comparison to the previous static location, and different location objectives have a substantial influence on location results. At the same time, the findings indicate that exploring the problem of enterprise location from a dynamic perspective could help reduce the operating cost and resources from a sustainable development perspective.

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Time, cost, quality, and safety, with mutual influence, are the four major control items for project management. The best solution for a project is to achieve high quality with low cost in a proper time limit and without safe accident. Based on the comprehensive limitations above, an integrated optimization model is build up, which can balance the construction time-cost-quality-safety systematically in different risk level in order to archive the most satisfactory goals or several approximately perfect plans as alternatives. Through the optimizing the overall economic benefit of construction project is enhanced. Finally an instance, office building project, is carried out to show the validity of the model.