No abstract

40 pregnant women with obesity were totally examined and their outcomes of pregnancy and delivery were controlled. The examination of all pregnant women included the comprehensive examination of the functional state of the hepatobiliary system, ultrasound examination of the liver to identify the liver steatosis. These medical examinations made possibility to assess the dynamics of a clinical picture, ultrasound conclusions, biochemical indicators of liver function and lipid metabolism during the treatment. The frequency and severity of obstetric complications were also assessed.

The article presents the features of the course of non-alcoholic fatty liver disease in obese patients, the mechanisms of this pathology and the impact of this condition during pregnancy. Much attention is paid to disorders of fat metabolism, which contribute to a complicated course of gestation, increasing the possibility of development of placental insufficiency, miscarriages, preeclampsia and generally have a negative impact on perinatal outcomes. Modern diagnostics and correction of these disorders are discussed.