The role of ABET accreditation system is quite significant in providing guidance towards program and course design. The program outcomes encompassing through knowledge, skill and attitude play an important role towards competency development of the students. To improve the employability quotient of these fresh graduates, the alignment of respective outcomes along with the base lined expectations of IT industry is needed. In this context Software Engineering (SE) plays an important role in the transformation journey of the graduates to become entry level developers. It also helps to bridge the gap between academia and IT industry so that these new hires are productive as soon as possible. In this paper, the expectations of an IT industry from the new hires is described in conjunction with ABET educational outcomes highlighting pedagogical aspects that enable students develop these abilities. SE course is used as vehicle and an approach is presented integrating software code of ethics (recommended by ACM -IEEE), SE principles, pedagogical aspects and assessment instruments. Subsequently experiences from our corporate learning environment are highlighted.
Cardiovascular diseases (CVD) are the major cause of death among people across the globe. Hypercholesterolemia is one of the major contributing factors for CVD. Molecules that bind with Lanosterol synthase enzyme, can be potential drug targets. Statin group of compounds like Simvastatin, cerivastatin, Atorvastatin etc., used for treating hypercholesterolemia have side effects and hence there is a growing demand for plant derived flavonoids. This work focusses on studying the compounds quercetin-3-O-(2??,6??-di-O-?-l-rhamnopyranosyl)-?-d-glucopyranoside, kaempferol-3-O-(2??,6??-di-O-?-l-rhamnopyranosyl)-?-d-glucopyranoside, rutin; quercetin-3-O-?-d-glucopyranoside (Iso quercetin); and kaempferol-3-O-?-d-glucopyranoside (Astragalin) present in Chenopodium album Linn to inhibit Lanosterol synthase. Bioactivity score, drug likeness character was assessed in silico. Based on bioactivity spectrum, it is observed that the molecules are biologically active and the probability of these compounds to be biologically active is ranging from 0.784 to 0.992, suggesting that these compounds are effective for treating hypercholesterolemia. In the molecular docking studies, the compounds binding affinity score was in agreement that the molecules have the potential to be used as an alternative to the statin group of compounds in treating cholesterol.
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