No abstract

A novel near-infrared fluorescent probe (L) based on a 1,4-diethyl-1,2,3,4-tetrahydro-7H-pyrano [2,3-g] quinoxalin-7-one scaffold has been synthesized and characterized. Probe L displays highly selective and sensitive recognition to H 2 S over various anions and biological thiols with a large Stokes shift (125 nm) in THF/H 2 O (6/4, v/v, Tris-HCl 10 mM, pH ¼ 7.4). This probe exhibits turn-on fluorescence for H 2 S through HS À induced thiolysis of dinitrophenyl ether. Confocal laser scanning micrographs of MCF-7 cells incubated with L confirm that L is cell-permeable and can successfully detect H 2 S in living cells.

A novel acylhydrazone derivative (i.e. fluorescence probe L) was designed and synthesized based on 7-hydroxytetrahydroquinoxaline-6-formaldehyde. Probe L can recognize for Al 3＋ with highly selectivity in DMSO/Tris (V∶ V＝7∶3) solution. When Al 3＋ is added into the solution of L, the fluorescence color of solution changes from non-fluorescence to purple red fluorescence, and the maximum emission wavelength of L is 640 nm within range of the near-infrared. Probe L possesses a large Stokes shift (170 nm) and the detection limit of L is 0.521 μmol/L. In addition, L can detect Al 3＋ in the real water samples and imaging for Al 3＋ in MCF-7 cells.