The interaction between each one of Trichomonas vaginalis and Tritrichomonas foetus with their hosts is a complex process in which components associated to the cell surfaces of both parasites and host epithelial cells, and also to soluble components found in vaginal/urethral secretions, are involved. Either cytoadhesion or the cytotoxicity exerted by parasites to host cells can be dictated by virulence factors such as adhesins, cysteine proteinases, laminin-binding proteins, integrins, integrin-like molecules, a cell detachment factor, a pore-forming protein, and glycosidases among others. How trichomonads manipulate informations from the extracellular medium, transduce such informations, and respond to them by stimulating the activities of some surface molecules and/or releasing enzymes are the aspects concerning trichomonal virulence which are here briefly reviewed and discussed.
Volume 4 -Issue 2 natural [1,6], however they do not take into account the thousands of years that have allowed the dog to differ from its ancestors by being domesticated, which through 36 changes in its genome regions, where 10 of these times can have a critical role in starch digestion and fat metabolism, that makes the feeding and even the life expectancy of dogs and wolves not the same [7]. B.A.R.F diets are foods that include a wide variety of ingredients, meat (chicken, pork, beef, fish, lamb), vegetables, fruits, eggs with or without shell, oils, dairy products, cereals, supplements, among others. All these ingredients are mixed by different processes and this allows raw meat diets to be offered in many commercial or homemade presentations [1,3,7]. Today this nutritional alternative in the city of Medellín, Colombia, has generated a large growing industry, where to date there are more than 30 companies that sell BARF diets. The components of these diets are prone to easy contamination with different bacterial and fungal agents that could have a pathogenic and toxic potential, not only for pets, but also for all people who handle these diets and are in contact with the animals that consume them [2,4,5].Proponents of BARF-type diets claim multiple benefits of these on the health of pets, such as strengthening the immune system, less presence of food allergies, canines and felines healthier, a longer life expectancy, better dental health, better coat and the skin [4,7,8].
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