Chronic pain (CP) is a severe clinical entity with devastating physical and emotional consequences for patients, which can occur in a myriad of diseases. Often, conventional treatment approaches appear to be insufficient for its management. Moreover, considering the adverse effects of traditional analgesic treatments, specialized pro-resolving lipid mediators (SPMs) have emerged as a promising alternative for CP. These include various bioactive molecules such as resolvins, maresins, and protectins, derived from ω-3 polyunsaturated fatty acids (PUFAs); and lipoxins, produced from ω-6 PUFAs. Indeed, SPMs have been demonstrated to play a central role in the regulation and resolution of the inflammation associated with CP. Furthermore, these molecules can modulate neuroinflammation and thus inhibit central and peripheral sensitizations, as well as long-term potentiation, via immunomodulation and regulation of nociceptor activity and neuronal pathways. In this context, preclinical and clinical studies have evidenced that the use of SPMs is beneficial in CP-related disorders, including rheumatic diseases, migraine, neuropathies, and others. This review integrates current preclinical and clinical knowledge on the role of SPMs as a potential therapeutic tool for the management of patients with CP.

Background: There is evidence of a high prevalence of depression and anxiety in university students. Therefore, college time is a key period where prevention of mental disorders through interventions that promote resilience and mental health can be relevant. Currently, there are interventions available, but these are insufficient for those who need them. Online interventions are tools that can facilitate global accessibility and are easy for young people to use. CORE (Cultivating Our Resilience) is a self-administered online program, based on Ryff's psychological wellbeing model, to promote resilience and coping skills in university students at risk of developing symptoms of depression or anxiety. The objective is to evaluate the effectiveness of this intervention protocol in comparison with an active control condition targeting healthy lifestyle, and a waiting list control condition. The study will be conducted in four populations of Spanish-speaking university students (Spain, Argentina, Colombia, and Mexico). Methods: The study design is a randomized controlled trial (RCT). At least 324 university students will be randomly assigned to three conditions: 1) CORE, a 6-week training program to improve resilience; 2) HLP, a 6-week training to promote a healthy lifestyle; and 3) WL, waiting list control condition. The primary outcome measure will be the Connor-Davidson resilience scale. Additionally, measures of anxiety, depression, quality of life and sociodemographic variables (age, sex, incomes, marital status, among others) will be collected. Participants will be evaluated at pre-treatment, after each module, 6 weeks after allocation, and at 3-month follow-up. Intention-to-treat and per-protocol analyses will be performed.

La violencia, además de considerarse como una condición inherente a las relaciones humanas, también se concibe como un problema de salud pública que afecta significativamente la salud mental de las personas implicadas. De hecho, son varios los estudios que reportan las implicaciones o secuelas psicológicas en combatientes y población civil expuesta a conflictos bélicos o similares que impliquen violencia. Algunas de las cifras exponen que hasta un 30% de las personas expuestas a violencia padecen síndrome de estrés postraumático y depresión, incluso se ha reportado un 100% en poblaciones con una afectación muy significativa (Larizgoitia et al., 2011). Por tanto, el abordaje psicológico, requiere competencias amplias que inscriban un campo de conocimiento inter o transdisciplinar que vincule las cualidades y procesos humanos, sus circunstancias vitales y contextuales en el tiempo y, particularmente, los recursos personales, familiares y comunitarios.

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Family communication establishes a vehicle for the transmission of information between family members and completely marks the nature and quality of family life. Family communication can be understood as an index of the climate and quality of the family system. La comunicación familiar establece un vehículo para la transmisión de información entre los miembros dela familia y marca por completo la naturaleza y la calidad de la vida familiar. La comunicación familiar puede entenderse como un índice del clima y la calidaddel sistema familiar.