Este artículo aborda los procesos de marcación social de lugares de memoria en Argentina, Chile y Colombia, y las acciones desarrolladas en estos espacios y desde ellos como parte de una función restitutiva del ámbito de lo político y lo comunitario. En los casos argentino y chileno, la recuperación de ex recintos de detención y tortura de las últimas dictaduras y su transformación en sitios de memoria ha posibilitado la ejecución de un trabajo de memoria que excede lo conmemorativo y reparatorio, mientras en Colombia la proliferación de lugares de memoria ha convocado la participación de actores locales que, desde ellos, rearticulan sentidos comunitarios destruidos o debilitados por la larga experiencia del conflicto armado. De distinta forma, estos espacios de memoria se proponen incidir en el escenario público en el cual se insertan, trascendiendo las fronteras topográficas del lugar, lo que permite entenderlos como espacios para una acción política con una capacidad de convocatoria de actores diversos.

No abstract

The developmental strategies used by progenitor cells to endure a safe journey from their induction place towards the site of terminal differentiation are still poorly understood. Here we uncovered a progenitor cell allocation mechanism that stems from an incomplete process of epithelial delamination that allows progenitors to coordinate their movement with adjacent extra-embryonic tissues. Progenitors of the zebrafish laterality organ originate from the surface epithelial enveloping layer by an apical constriction process of cell delamination. During this process, progenitors retain long-term apical contacts that enable the epithelial layer to pull a subset of progenitors along their way towards the vegetal pole. The remaining delaminated progenitors follow apically-attached progenitors' movement by a co-attraction mechanism, avoiding sequestration by the adjacent endoderm, ensuring their fate and collective allocation at the differentiation site. Thus, we reveal that incomplete delamination serves as a cellular platform for coordinated tissue movements during development.

The developmental strategies used by progenitor cells to allow a safe journey from their induction place towards the site of terminal differentiation are still poorly understood. Here we uncovered a mechanism of progenitor cell allocation that stems from an incomplete process of epithelial delamination that allows progenitors to coordinate their movement with adjacent extra-embryonic tissues. Progenitors of the zebrafish laterality organ originate from the superficial epithelial enveloping layer by an apical constriction process of cell delamination. During this process, progenitors retain long-lasting apical contacts that enable the epithelial layer to pull a subset of progenitors on their way to the vegetal pole. The remaining delaminated cells follow the movement of apically attached progenitors by a protrusion-dependent cell-cell contact mechanism, avoiding sequestration by the adjacent endoderm, ensuring their collective fate and allocation at the site of differentiation. Thus, we reveal that incomplete delamination serves as a cellular platform for coordinated tissue movements during development.