The aim was to assess how accurately some commonly used risk factors/risk markers (predictors) for caries development could identify children with and without approximal caries as judged from bitewing radiography. Two hundred and sixty-seven consecutive 5-year-old children from two Swedish cities participated. Three experienced dentists examined the children. The predictors were the overall dmfs (decayed, missing and filled surfaces) value (canines and molars), the number of occlusal dmfs, the frequency of intake of between-meal sugary products, visible plaque on free smooth surfaces of second primary molars, toothbrushing habits and (before bitewing examination) an overall judgement by the examining dentist. The mean dmfs value without bitewing examination was 0.40 (SD = 1.22). Twelve percent of the children had at least one dentin lesion and 33% at least one enamel lesion that were detected from bitewing examination only. The gain from adding bitewing examination to clinical examination amounted to a mean of 1.2 approximal enamel and/or dentin lesions. The ability to correctly identify children with approximal caries from the predictors was limited; sensitivity ranged from 0.27 to 0.75 and specificity ranged from 0.41 to 0.93. The single best predictor was the dentist’s overall judgement with an average precision of 73%; average sensitivity for the presence of enamel and dentin lesions was 0.48 and for the presence of dentin lesions 0.66. The rest of the predictors added little to the predictive power. It is concluded that 33% of the 5-year-olds, representing a low caries prevalence population, benefited from bitewing examination. The ability to identify these children from the predictors was, however, limited.

This study was undertaken to examine the effects of intubation on the enamel development of primary teeth in children intubated during the first 3 months of life. The teeth of 35 children were examined clinically for signs of defects. Dental enamel defects were seen in 26 (74%) patients; enamel hypoplasia was seen in 15 and enamel hypomineralization in 19 cases. In eight patients both enamel hypoplasia and hypomineralization were found. There was a preponderance of enamel defects in the right maxilla, which supports the hypothesis that an early trauma to mineralizing primary teeth caused by laryngoscope may lead to dental enamel hypoplasia.

The purpose of this investigation was to study the relationship between low values of blood ionized calcium measured in the first days of life postpartum and the clinical and histologic appearance of enamel of primary teeth. Twenty‐five healthy children selected on the basis of optimality with known blood values of ionized calcium from the first days of life participated in a dental examination at the age of 5 yr. Twenty‐four of the children contributed one exfoliated tooth each, which was histologically examined. The infants had lower mean values of ionized blood calcium on days 1 and 3 than day 5 postpartum. Thirteen of the 25 children had enamel aberrations, mainly on one tooth each. The histologic examination showed normal overall enamel morphology. The neonatal line was present in all teeth, and these lines were mostly thin. The registered findings about the enamel morphology could not, in any case, be correlated with the measured values of neonatal blood ionized calcium.

Clinical and histologic appearance in enamel of primary teeth from children with neonatal hypocalcemia induced by blood exchange transfusion, Acta Odontologica Scandinavica, 53:2, 123-128 To link to this article: http://dx.Ranggird L, Ostlund J, Nelson N, Nortn JG. Clinical and histologic appearance in enamel of primary teeth from children with neonatal hypocalcemia induced by blood exchange transfusion. Acta Odontol Scand 1995;30:122-128. Oslo. ISSN 0001-6357. ACTA ODONTOL SCANT) 53 (1995) -1 1 -ET days Hypocal. a 2 3 3 days X X X X X X X X Gat. age S 36 weeks

Abstract— Tetracycline in low dose is often used as a marker in hard tissue research. A low dose effect on enamel formation has never been proven despite well known toxic reactions in enamel after higher doses. The purpose of the investigation was to evaluate enamel formation in maxillary incisors of rats given a single low dose of a tetracycline with low toxicity, commonly used in research. Eight young rats received an intraperiotonal injection of 2 mg oxytetracycline per 100 g. The rats were terminated after periods between 1 h until 5 days. Undemineralized ground sections were prepared and studied under fluorescence microscopy. Microradiograms were taken to study the degree of mineralization. A diffuse uptake was seen within enamel in areas corresponding to late secretory stage and incisally in maturing enamel with a low mineralization degree. Tendencies of enamel aberrations were seen in all rats. These appeared as splittings within the formed enamel. In conclusion, low toxicity tetracycline disturbs normal amelogenesis, even if administered in low doses. It should therefore be avoided in hard tissue research where enamel formation is studied.