This experimental paper deals with phase separations of binary mixtures composed of a continuous liquid crystal phase and an isotropic dispersed phase. In contrast to isotropic binary mixtures, the investigated mixtures do not lead to a full phase separation but to a self-ordering of colloidal particles, as reported earlier (Loudet, J. C. et al. Nature 2000, 407, 611). We present here further aspects of such phase separations which include the kinetics of the phase separation, the origin of the formation of dislocation-like patterns, the influence of surfactants, chiral additives, and temperature on the formed colloidal structures. The present results show that (i) the dislocations in chain arrays can be seen as kinetically frozen defects, (ii) temperature can be used to control the size of the domains formed upon demixing, (iii) a slight change in surface chemistry, via the addition of surfactants, profoundly alters the formed colloidal structures, and (iv) chiral additives allow the formation of unique helical pearl chains which reflect the symmetry of the liquid crystal phase they are embedded in.