Present study was undertaken to evaluate the effect of zinc supplementation on growth performance
and nutrient utilization in kids. Twenty four goat kids (4-6 month age) were randomly divided into 4 groups (T1, T2, T3 and T4) having 6 kids each. Kids in the group T1 were fed basal diet which
contained 29.02 mg Zn/kg DM from ingredients of ration without any additional Zn supplementation.
Kids in the T2, T3 and T4 groups were fed the same basal diet with additive 20, 50 and 100 ppm
Zn (as ZnSO4) in their diets, respectively. The study was conducted for 90 days. Digestion trial of
7 days was conducted towards the end of experiment to assess the digestibility of the nutrients.
Results indicated significantly higher average body weight gain, crude protein (CP) digestibility and
better feed efficiency in kids fed diet supplemented with 50.0 mg Zn/kg DM. From the results it
was concluded that the Zn supplementation @ 50.0 mg/kg DM in basal diet significantly improved
body weight (BW) gain, CP digestibility and feed efficiency ratio (FER) of kids.
A study was conducted on 20 young healthy male patients to compare the antibiotic serum levels and urinary excretion of tetracycline and oxytetracycline after two 500-mg doses daily for 5 days. After a single dose of 500 mg, the serum antibiotic levels of tetracycline and oxytetracycline were almost similar for the next 12 h and were still significantly higher than the minimum inhibitory concentration (0.5 μg/ml). In contrast, 5 days study of serum antibiotics revealed very significantly elevated tetracycline levels compared to oxytetracycline. Tetracycline also showed a higher cumulative effect after stoppage of therapy for the next 36 h against 24 h in the case of oxytetracycline. Urinary excretion studies have shown that oxytetracycline is excreted more rapidly and in higher concentration than tetracycline and this may account for superiority of oxytetracycline for treatment of urinary tract infections.
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