Purpose The purpose of this in vitro study was to evaluate the effect of software on scan time, trueness, and precision of digital scans created using the CEREC Omnicam. Material and methods Sixty scans (20 scans/provider) of a standard reference cast were made by three different providers using the CEREC Omnicam with both CEREC Ortho 1.2.1 software (10 scans/provider) and CEREC SW 4.4.4 software (10 scans/provider). A digital full arch scan and the time to complete each scan were recorded. Trueness was calculated by overlaying the digital scans against a reference file created using the standard reference cast and a laboratory‐based, white light, 3‐dimensional scanner. Precision was calculated by overlaying each of digital scans against each other, using each scan as a reference. The non‐parametric Mann‐Whitney U‐test was used to determine significant differences attributable to scanning software for each provider. Results The CEREC Ortho 1.2.1 software required a longer scan time than the CEREC SW 4.4.4 software for each provider (∼1 minute). No significant difference in trueness was observed within one provider. Two individual providers had higher precision when scanning with the CEREC Ortho 1.2.1 software than the CEREC SW 4.4.4 software. Conclusion Software and scan strategy may affect the accuracy of complete‐arch scans. The CEREC Ortho 1.2.1 software may demonstrate a speed‐accuracy tradeoff, with generally longer scan times and possibly more precise scans.