No abstract

MRI was significantly superior to CT in the diagnosis of bone swelling, PLC injury, disk herniation, spinal canal compression, spinal cord contusion and swelling present in SCT. MRI detected a larger number of lesions than CT and is highly useful for the diagnosis of soft tissue and intrathecal injuries.

Objective To present a surgical series of patients with low grade temporal gliomas causing intractable epilepsy, focusing on long-term seizure outcome.Method A retrospective study was conducted with patients with temporal low-grade gliomas (LGG).Results Sixty five patients with were operated in our institution. Males were more affected than females and the mean age at surgery was 32.3 ± 8.4 (9-68 years). The mean age at seizure onset was 25.7 ± 9.2 (11-66 years). Seizure outcome was classified according with Engel classification. After one year of follow up, forty two patients (64.6%) were Engel I; seventeen (26.2%) Engel II; four (6.2%) Engel III and two (3.1%) Engel IV. Statistically significant difference in seizure outcome was obtained when comparing the extension of resection. Engel I was observed in 39 patients (69.6%) with total resection and in only 3 (33.3%) patients with partial resection.Conclusion Gross-total resection of temporal LGGs is a critically important factor in achieving seizure-freedom.

Objective: To investigate the influence of patient's age and seizure onset on surgical outcome of temporal lobe epilepsy (TLE). Method: A retrospective observational investigation performed from a cohort of patients from 2000 to 2012. Results: A total of 229 patients were included. One-hundred and eleven of 179 patients (62%) were classified as Engel I in the group with , 50 years old, whereas 33 of 50 (66%) in the group with $ 50 years old group (p = 0.82). From those Engel I, 88 (61%) reported epilepsy duration inferior to 10 years and 56 (39%) superior to 10 years (p , 0.01). From the total of patients not seizure free, 36 (42%) reported epilepsy duration inferior to 10 years and 49 (58%) superior to 10 years (p , 0.01). Conclusion: Patients with shorter duration of epilepsy before surgery had better postoperative seizure control than patients with longer duration of seizures.Keywords: temporal lobe epilepsy, age at surgery, epilepsy duration, seizure outcome. RESUMOObjetivo: Investigar a influência da idade no momento da cirurgia e duração das crises no resultado cirúrgico da epilepsia do lobo temporal (ELT). Método: Estudo observacional retrospectivo de uma coorte de pacientes de 2000 a 2012. Resultados: Um total de 229 pacientes foram incluídos. Cento e onze de 179 pacientes (62%) foram classificados como Engel I no grupo com , 50 anos de idade, ao passo que 33 de 50 (66%) no grupo com $ 50 anos grupo de idade (p = 0,82). Daqueles Engel I, 88 (61%) relataram a duração da epilepsia inferior a 10 anos e 56 (39%) superiores a 10 anos (p , 0,01). Do total de pacientes não sem crises, 36 (42%) relataram a duração da epilepsia inferior a 10 anos e 49 (58%) superior a 10 anos (p , 0,01). Conclusão: Pacientes com menor duração da epilepsia antes da cirurgia tem melhor controle das crises pós-operatório.Palavras-chave: epilepsia do lobo temporal, idade no momento da cirurgia, duração da epilepsia, controle das crises.Epilepsy is the most common chronic neurological disease, affecting 0.4% to 1% of the general population. The cumulative incidence of seizure is thought to be approximately 10% to age 74 years, and the lifetime likelihood of receiving a diagnosis of epilepsy is almost 3% 1 . Temporal lobe epilepsy (TLE) is the most common epilepsy syndrome and affects almost 40% of epilepsy patients. Several risk factors are associated with epilepsy, such as prolonged childhood febrile seizure, status epilepticus, central nervous system (CNS) infections, head trauma, neoplasm, perinatal/vascular insults, mesial temporal lobe sclerosis (MTS), and a family history of epilepsy 2,3,4 . These risk factors are thought to cause brain injury at a molecular level, leading to either biologic or morphologic changes over years, ultimately leading to the development of refractory epilepsy 5 . Epilepsy surgery has been shown to be an effective treatment, especially for patients with refractory TLE associated with MTS (TLE-MTS), and 60% to 70% experience seizure remission 6,7,8,9 . Therefore, determining presurgical prognost...