Laryngeal papillomatosis is a rare disease of viral etiology that can obstruct the airway. Symptomatic treatment is essentially surgical. Anesthetic management needs special attention due to a narrow airway that will be shared with the surgical team. We discuss the perioperative management of a child with recurrent papillomatosis and possible strategies to manage similar cases.

Introduction: Perioperative anaphylaxis is a rare but serious, life-threatening condition that presents challenges in diagnosis and management. The incidence of severe perioperative reactions is estimated to be approximately 1:7,000–10,000. Case report: A 75-year-old patient underwent a surgical procedure due to adhesions of previous surgeries. She had a serious anaphylactic reaction in the intraoperative period, which was quickly addressed with fluid and adrenaline administration. Discussion: Proper management involves both immediate stabilization of the patient and identification of the causing agent. This identification is essential to avoid the recurrence of the event in other surgeries. A previous history of perioperative hypersensitivity reaction is the main risk factor for anaphylaxis.