A case is presented of a 48-year-old patient, with a 28-year history of Crohn’s disease, with chronic constipation with outlet obstruction symptoms due to the presence of a mucosal bridge at the low rectum. Endoscopic treatment was performed with section of the bridge, without any complications, and with immediate resolution of the symptoms.
Desarrollo de infección tuberculosa latente y efectos adversos de la isoniazida durante tratamiento con biológico por Enfermedad de Crohn Development of latent tuberculosis and adverse effects with isoniazid during biologist therapy´s in Crohn´s Disease Desenvolvimento de tuberculose latente durante e efeitos adversos da isoniazida o tratamento com biológicos para a Doença de Crohn Resumen Los fármacos anti factor de necrosis tumoral alfa (TNF-a) bloquean una de las citoquinas implicadas en la patogénesis de la Enfermedad Inflamatoria intestinal (EII). Su uso se relaciona con aumento de tuberculosis (TB), por lo que el despistaje previo es obligatorio. En la infección tuberculosa latente (ITBL) se utiliza isoniazida como quimioprofilaxis, fármaco que no se encuentra libre de reacciones adversas. Se presenta y discute el caso de una paciente con reacción adversa en piel secundaria al uso de isoniazida. Palabras clave Anti factor de necrosis tumoral alfa, isoniazida; enfermedad inflamatoria intestinal, tuberculosis.
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