Analysis 2.4. Comparison 2 TRIFLUOPERAZINE versus TYPICAL ANTIPSYCHOTICS, Outcome 4 Global state: 1e. No substantial improvement-subgroup analysis-mixed diagnoses vs schizophrenia only.

Forty Wistar-Tecpar rats were used to determine the performance of polyglecaprone 25 sutures in the abdominal wall, contaminated or not. The animals were anesthetized and polyglecaprone 25 was implanted into the ventral abdominal wall on the left side and compared to the use of plain catgut implanted on the right. The subcutaneous tissue of 20 animals was contaminated with a standardized Staphylococcus aureus solution and the remaining 20 animals were not contaminated. The animals were checked on the third and seventh day after implant and the tissue reaction caused by polyglecaprone 25 in the presence or absence of contamination was found to be significantly less intense.

Background: Different lesions may affect the liver resulting in harmful stimuli. Some therapeutic procedures to treat those injuries depend on liver regeneration to increase functional capacity of this organ. Aim: Evaluate the effects of tranexamic acid on liver regeneration after partial hepatectomy in rats. Method: 40 rats (Rattus norvegicus albinus, Rodentia mammalia) of Wistar-UP lineage were randomly divided into two groups named control (CT) and tranexamic acid (ATX), with 20 rats in each. Both groups were subdivided, according to liver regeneration time of 32 h or seven days after the rats had been operated. The organ regeneration was evaluated through weight and histology, stained with HE and PCNA. Results: The average animal weight of ATX and CT 7 days groups before surgery were 411.2 g and 432.7 g, and 371.3 g and 392.9 g after the regeneration time, respectively. The average number of mitotic cells stained with HE for the ATX and CT 7 days groups were 33.7 and 32.6 mitosis, and 14.5 and 14.9 for the ATX and CT 32 h groups, respectively. When stained with proliferating cell nuclear antigen, the numbers of mitotic cells counted were 849.7 for the ATX 7 days, 301.8 for the CT 7 days groups, 814.2 for the ATX 32 hand 848.1 for the CT 32 h groups. Conclusion: Tranexamic acid was effective in liver regeneration, but in longer period after partial hepatectomy.

No relation between histological modification and tibolone treatment was verified after short-, medium- and long-term treatment.