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Objective: to analyze the knowledge of students of the Undergraduate Nursing Course of a Private Higher Education Institution in Belem, State of Pará, Brazil on Basic Life Support. Method: A cross-sectional, descriptive, exploratory study with a quantitative approach was carried out from September to October 2018. Result: In the evaluation of knowledge about Basic Life Support, on a scale of 0 to 100 points, it was verified that the lowest grade was 20.6 points and the highest was 90.4. The mean was 63.5 points, with a standard deviation of 15.5. The median was 64 points, with the interquartile deviation of 20 points (54 to 74 points). It was evidenced that 62% of the students had a grade lower than 70 points. And 19% scored less than 50 points. The population studied has reduced, and sometimes inadequate, knowledge about cardiorespiratory arrest and cardiopulmonary resuscitation, which may compromise the care provided, leading to damages to resuscitation and, consequently, to contribute to the appearance and / or aggravation of sequels, impacting on increased morbidity and mortality. Conclusion: it is understood that it is fundamental to establish training and evaluation of these, in a theoretical and practical, as a way to optimize and consolidate knowledge even during academic training.