Total phenolic content (TPC), total flavonoid content (TFC), antioxidant and antimicrobial in vitro activity of ethanolic (EE) and hydroethanolic (HE) extracts of mango peel Ataulfo were evaluated. The highest TPC, TFC and antioxidant capacity were as shown in EE. Ethanolic extract was incorporated into ground beef at 1000 (BBEA) and 2000 mg/kg meat (BEEB) concentrations and then compared with 250 mg of sodium ascorbate/kg meat (ASC) along with a control (without antioxidant). The effects of adding EE on instrumental colour, metmyoglobin content, thiobarbituric acid reactive substances (TBARS), pH, microbial load and sensorial analysis of ground beef were evaluated for 11 days at 4 °C. BEEB added in raw ground beef improved colour stability while the lipid oxidation in raw and raw-cooked ground beef was inhibited with a greater antioxidant effect than ASC and a similar overall acceptability score (cooked ground beef). However, incorporating BEEB into ground beef did not show significant antimicrobial activity. Therefore, mango peel extracts could potentially be used as a natural antioxidant in ground beef.

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This paper considers the problem of making statistical inferences about a parameter when a narrow interval centred at a given value of the parameter is considered special, which is interpreted as meaning that there is a substantial degree of prior belief that the true value of the parameter lies in this interval. A clear justification of the practical importance of this problem is provided. The main difficulty with the standard Bayesian solution to this problem is discussed and, as a result, a pseudo-Bayesian solution is put forward based on determining lower limits for the posterior probability of the parameter lying in the special interval by means of a sensitivity analysis. Since it is not assumed that prior beliefs necessarily need to be expressed in terms of prior probabilities, nor that post-data probabilities must be Bayesian posterior probabilities, hybrid methods of inference are also proposed that are based on specific ways of measuring and interpreting the classical concept of significance. The various methods that are outlined are compared and contrasted at both a foundational level, and from a practical viewpoint by applying them to real data from meta-analyses that appeared in a well-known medical article.

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