Silicone injections, although well known for their adverse effect, are still widely used around the world. Pneumonitis after an injection of silicone liquid has been reported in several patients. Silicone liquid injection is frequently administered to transgender individuals into the buttocks area but is rarely used for the breasts. We report a case of presumed pneumonitis following breast silicone liquid injection. A 36‐year‐old woman was admitted due to shortness of breath three days after silicone liquid injection. Chest X‐rays (CXR) showed bilateral alveolar patchy infiltrates. Chest computed tomography scan revealed diffuse infiltrates involving mostly peripheral lung fields (suggestive for silicone liquid injection) and multiple isodense soft‐tissue nodules in both breasts. The treatment included antibiotic and steroid administration. After being treated for a week, clinical results and the latest CXR revealed improvement compared with the previous CXR, and the patient was discharged in good condition.

HighlightsThis is an extremely rare case and quite challenging both to diagnose and to treat.Immunostaining is sometimes needed to confirm the diagnosis.Contrary to most similar reported case, the tumor recurred after surgery.Although rarely needed, chemotherapy may successfully prevent tumor progression.

A 12‐year‐old boy presented with progressive disability to walk for four months, which was so severe that he could no longer perform daily activities. No respiratory symptom was found. On physical examination, there was a soft tissue mass in the thoracic vertebrae. Physiological reflexes of both limbs were diminished. Tuberculin skin test was positive with a 12 mm induration. Magnetic resonance imaging (MRI) of the spine showed a kyphotic cervico‐thoracal region with predominantly anterior paravertebral mass that was enhanced with contrast, compressing the spinal cord at level Th‐3 and Th‐4, suggestive of tuberculous spondylitis. He was treated with regular anti‐tuberculosis drugs. In the first four months, he began being able to sit, and two months later, he could walk again. After 12 months of treatment without surgery, MRI showed no more compression of the spine and remarkable resolution of paravertebral soft tissue mass. He then resumed his daily life again.