No abstract

Abnormalities of thyroid hormone status are common in severe psychiatric disorders. The purpose of this study was to stratify and compare thyroid hormone levels associated with schizophrenia and bipolar disorder and to evaluate their changes in the Latin American population. The study was retrospective. Statistical results were based on systematic analysis. A descriptive analysis of thyroid tests and clinical characteristics was performed. Thyroid function data were obtained from the records of 343 patients, 18 of whom were positive for anti-TPO. Abnormal thyroid hormone status in general and the presence of hypothyroidism and hyperthyroidism, in particular, were found in 29,3 %, 25,17 %, and 4,08 % of schizophrenia patients, respectively. There were no gender differences. Conclusions: Thyroid changes were found in patients with schizophrenia and bipolar affective disorder. These results highlight the importance of studying special populations with organic mental illnesses, such as schizophrenia, rather than focusing only on bipolar disorders, to achieve better characterization.

Introduction: Adverse events related to vaccines are reactions that can lead to serious complications, in the present that we live at the publication of this article with the need to generate high rates of vaccination have been presented in the case of vaccine agents against COVID-19 adverse events, with thrombotic events being the most important. Case Presentation: This is a 37-year-old female patient who presents 11 days after ChAdOx1-S vaccination against COVID-19 presents with intense headache associated with symptoms of intracranial hypertension, she was initially taken to simple cranial tomography showing presence of cerebral edema and indirect signs of cerebral venous thrombosis, it is proposed to carry out cerebral angiography which showed the presence of thrombosis of both transverse venous sinuses, no hypercoagulability states were found in the laboratories, the immunological tests carried out for antiphospholipid syndrome were negative, the thrombotic event was associated with the ChAdOx1-S vaccine, later the patient was taken to thrombectomy by Neuroradiology, achieving complete channeling of both transverse venous sinuses. Conclusions: Adverse events associated with vaccination have been described with multiple vaccine agents, this component against COVID-19 is also an event to consider, knowing the pathophysiology of these events is essential to be able to reduce these risks and select the least risky agent. Despite this risk, vaccination remains the only cost-effective measure to reduce the morbidity and mortality associated with COVID-19.

La colecistectomía tiene un excelente resultado terapéutico. Sin embargo, hasta un 15-20 % de los pacientes colecistectomizados continúan teniendo una variedad de síntomas gastrointestinales. El síndrome poscolecistectomía (SPC) se puede definir como síntomas de cólico biliar o dolor abdominal persistente en el cuadrante superior derecho (CSD) con o sin dispepsia, que son similares a los experimentados por el paciente antes de la colecistectomía. Los SPC siguen estando presentes como un reto diagnóstico y terapéutico. El objetivo de este artículo fue revisar críticamente la literatura sobre la magnitud del problema y las posibles explicaciones fisiopatológicas del SPC.