Resumen El presente artículo analiza la violencia en el noviazgo mediante el estudio de sus tasas de prevalencia en Latinoamérica y Chile en las dos últimas décadas, comparándolas con los datos procedentes de otros países. Se constata la relevancia del problema en este último país, donde se llega al 51% en violencia psicológica y al 25% en la física. Se exponen además posibles causas de la poca relevancia y difusión de este problema en las políticas públicas, comparando metodologías e instrumentos de evaluación utilizados. Palabras clave: violencia en el noviazgo, prevalencia de violencia, salud mental juvenil.
Pueraria lobata, also known as Kudzu (Japan) or Ge (China), is a medicinal plant widely used in Oriental traditional medicine. In this study the development, optimization and validation of an HPLC ethod for quality control of Pueraria flower plant material is presented. By means of this analytical method the three major compounds, i. e., the isoflavones tectorigenin 7- O-[beta- D-xylopyranosyl-(1 - 6)-beta- D-glucopyranoside], tectorigenin 7- O-beta- D-glucopyranoside and tectorigenin, were quantified, using the isoflavones genistin and genistein as external standards. The extraction procedure, the extraction solvent, the extraction yields and the HPLC conditions were evaluated and optimized. The samples were analyzed on an RP C18 column, and eluted with a binary system consisting of water and methanol using a linear gradient; detection was at 262 nm. Tectorigenin used in the recovery experiments was isolated and purified in the laboratory. The final method was fully validated according to the ICH guidelines in terms of linearity, precision and accuracy. The validation data showed that the precision, (RSD% (betweendays) of 3.1, 2.84 and 1.77 for the three major compounds, respectively), and the accuracy (recovery of 104.2 %) were acceptable. These validation results demonstrate the suitability of the method for the quality control of this crude drug.
Dental education includes the development of manual skills to perform tasks needed to train students to drill for the elimination of caries or for restorative purposes. 1 Historically, cadaver teeth have been used to train dental students in these drilling procedures but, for ethical, legal and biological reasons, 2 they have been replaced by artificial teeth made of plastic. 1,3 Contemporary technology allowed the development of haptic virtual simulators (HVS); in recent years, their use has been growing exponentially in medical and dental education. 4-6 High-fidelity simulators can be an interactive didactic tool that allows students to perform certain professional tasks in a safer and more controlled environment. This performance requires the mobilisation and integration of their knowledge and skills in order to solve simulated clinical situations. 1-3 Also, the combined use of both HVS and conventional Phantom-head systems improves spatial
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