Aim To determine the prevalence of early childhood caries (ECC) and investigate the effect of associated risk factors on ECC prevalence in preschool children in Riyadh, Saudi Arabia. Methods This cross-sectional study included Saudi preschoolers aged 36–71 months. Parents/guardians completed a structured, self-administered questionnaire assessing sociodemographics; medical, dental, and dietary history; and oral hygiene practices. Children were orally examined for dental caries, oral hygiene, and plaque deposition. Results A total of 383 children were examined. ECC prevalence was 72.6%, with a mean decayed, missing, and filled teeth (dmft) score of 4.13 (±3.99) and a mean decayed, missing, and filled surfaces (dmfs) score of 7.0 (±9.1). Children from schools in northern Riyadh and those of fathers in professional jobs were less likely to have ECC [(OR: 0.203; 95% CI: 0.082–0.503)] and [(OR: 0.472; 95% CI: 0.256–0.871)], respectively. Children with a nocturnal feeding history and poor oral hygiene were more likely to have ECC [(OR: 2.281; 95% CI: 1.143–4.553)] and [(OR: 5.523; 95% CI: 2.269–13.441)], respectively. Conclusions The prevalence of ECC in preschool children in Riyadh is high and affected by parental socioeconomic factors, infant feeding practices, and children’s oral hygiene status.

Dental caries is primarily elicited by modifiable factors such as inadequate oral hygiene, poor dietary practices and deficient fluoride exposure. However, there is a growing body of evidence suggesting the profound influence of genetic factors in dental caries susceptibility. The present study aimed to evaluate the association between single nucleotide polymorphisms (SNPs) in ENAM (rs12640848), MMP20 (rs1784418), TAS2R38 (rs713598), and LTF (rs4547741) genes and early childhood caries (ECC) in Saudi preschool children . This case-control study enrolled 360 Saudi preschool children (262 with ECC and 98 caries-free). Data on environmental factors were collected through a questionnaire. However, caries experience and oral hygiene data were obtained during clinical examination. Buccal swab samples were collected for DNA extraction and SNPs were genotyped using PCR and DNA sequencing. Children with ECC were compared to caries free children (control), then they were categorized into two categories based on ECC severity as follows; non-severe ECC (NS-ECC), and severe-ECC (S-ECC). Association between the SNPs, ECC, NS-ECC, and S-ECC was reported as an odds ratio (OR) with a 95% confidence interval (CI). The majority of the children (72.8%) exhibited ECC (31.7% NS-ECC and 41.1% S-ECC) with mean dmft of 4.20 ± 4.05. Multivariate analyses of environmental factors showed that nocturnal feeding was a risk factor for ECC ( P = 0.008). Poor oral hygiene was also a risk factor for both NS-ECC and S-ECC (ECC: P < 0.0001, NS-ECC: P = 0.032 and S-ECC: P < 0.0001). Univariate analysis showed that the AG genotype of rs1784418 of MMP20 gene was protective against ECC (OR = 0.532; 95% CI = 0.316–0.897, P = 0.018) and against NS-ECC (OR = 0.436; 95% CI = 0.238–0.798, P = 0.007). When environmental risk factors for ECC were included as covariates during multivariate analysis, AG variant in rs1784418 of MMP20 gene remained less frequent in NS-ECC cases compared to controls with borderline significance (OR = 0.542; 95% CI = 0.285–1.033, P = 0.063). Our findings concluded that MMP20 rs1784418 SNP might be associated with protection against ECC in Saudi preschool children.

Background: The single most chronic disease impacting children on an international scale is dental caries; there are alerts to deaths of children as a result of the complications caused by dental caries, despite the fact that this disease is completely preventable. This study aims to evaluate physicians’ dental knowledge, preventive measures they would provide and their referral patterns to paediatric dentists.Methods: A cross-sectional survey was conducted in Riyadh, Saudi Arabia. Certified paediatricians and general practitioners (GPs) from different sectors were invited to participate. The survey comprised 24 questions, distributed into 5 sections; demographic data, dental knowledge, participation in oral preventive measures, case scenarios and one question about participants’ opinion in implementing oral health rotations in the paediatric residency program. Results: 406 physicians participated in the study. Only 4.4 % of the participants answered all the knowledge questions correctly, the mean correct knowledge score was 2.95 ± 0.9937 out of 5. No significant difference was detected in the total knowledge score according to gender (P= 0.315), specialty and years of experience (P= 0.463 and 0.985 respectively). Common causes for referral were dental pain or swelling (67%) followed by a child with dental caries (43.6%). Less than 60% of the respondents would refer children to any dentist in the same hospital, while only 28 % only advise parents to consult a dentist. Most physicians suggested the addition of an oral health rotation in the medical residency program.Conclusions: The current level of oral health knowledge is not satisfactory to provide effective paediatric patients referrals to dentists, although their attitude towards providing oral preventive measures is good. Oral health knowledge and engagement should be emphasized in medical schools. Early and correct referral can be effective in preventing oral disease. The integration of oral health in undergraduate and specialty training curricula is vital to achieve disease prevention goals.