This study assessed the effect of e-taxation on revenue generation in Anambra state. Specifically, the study intends to; examine the effect of e-taxation on tax revenue generation in Anambra state; determine whether the adoption of etaxation has reduced tax malpractice in Anambra state and ascertain the tax revenue improved based on the e-taxation adoption in Anambra state. Survey design was employed. Data collected were analyzed and one sample t-test was used to test the formulated hypotheses. The study found that E-taxation has effect on tax revenue generation in Anambra state and adoption of e-taxation has reduced tax malpractice in Anambra state. Another finding is that tax revenue has improved based on the adoption of e-taxation in Anambra state. Based on this, the researchers recommended among others that well-equipped database on tax payers should be established by the governments with the aim of identifying all possible sources of income of tax payers for tax purpose.