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Large natural gas pipeline network optimization with the discrete variables is a question of the nonlinear optimized. Operating agencies have to ensure maximization of the business sector efficiency according the different resource conditions, the selling price and user requirements by the optimization. Based on the analyzing of the GA, SA algorithm's decision variables and the implementation process, a mathematical optimization model is put forward, using GASA combined algorithm, and it applied to carry out the optimization of a large-scale gas pipeline network with 98 nodes, the results shown that the GASA is more reasonable for the pipeline networks with better precision.

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