Omitting arm raising results in lower but acceptable image quality and a substantially higher effective radiation dose. Hence, effort should be made to position the arms above the shoulder when scanning trauma patients. Clinical trial registration no. NCT00228111.
Objectives To evaluate the technical performance of an ultra-high-resolution CT (UHRCT) system. Methods The physico-technical capabilities of a novel commercial UHRCT system were assessed and compared with those of a current-generation multi-detector (MDCT) system. The super-high-resolution (SHR) mode of the system uses 0.25 mm (at isocentre) detector elements (dels) in the in-plane and longitudinal directions, while the high-resolution (HR) mode bins two dels in the longitudinal direction. The normal-resolution (NR) mode bins dels 2 × 2, resulting in a del-size equivalent to that of the MDCT system. In general, standard procedures and phantoms were used to perform these assessments.Results The UHRCT MTF (10% MTF 4.1 lp/mm) is twice as high as that of the MDCT (10% MTF 1.9 lp/mm), which is comparable to the MTF in the NR mode (10% MTF 1.7 lp/mm). The width of the slice sensitivity profile in the SHR mode (FWHM 0.45 mm) is about 60% of that of the MDCT (FWHM 0.77 mm). Uniformity and CT numbers are within the expected range. Noise in the high-resolution modes has a higher magnitude and higher frequency components compared with MDCT. Low-contrast visibility is lower for the NR, HR and SHR modes compared with MDCT, but about a 14%, for NR, and 23%, for HR and SHR, dose increase gives the same results. Conclusions HR and SHR mode scanning results in double the spatial resolution, with about a 23% increase in dose required to achieve the same low-contrast detectability. Key Points • Resolution on UHRCT is up to twice as high as for the tested MDCT.• With abdominal settings, UHRCT needs higher dose for the same low-contrast detectability as MDCT, but dose is still below achievable levels as defined by current diagnostic reference levels. • The UHRCT system used in normal-resolution mode yields comparable resolution and noise characteristics as the MDCT system.
In-vivo thrombus compressibility varied from patient to patient, and this variation was irrespective of aneurysm size, pulse pressure, and thrombus volume. This suggests that thrombus might act as a biomechanical buffer in some, while it has virtually no effect in others. Whether differences in thrombus compressibility alter the risk of rupture will be the focus of future research.
ulmonary embolism (PE) represents a prevalent acute cardiovascular condition that has considerable morbidity and mortality and requires prompt diagnosis and treatment (1). Since 2007, multidetector CT pulmonary angiography has been the standard technique used to detect PE (2), achieving sensitivity and specificity (3-5) higher than 90% with state-of-the-art equipment (6). A missed PE carries a high potential risk for a future venous thromboembolism. On the other hand, false-positive results and subsequent anticoagulation treatment can result in complications (7). The potential for overdiagnosis of PE is as harmful as underdiagnosis (8).Iodine maps depict abnormalities that correspond to loss of blood flow caused by an acute (or chronic) PE (9-12). Iodine maps improve sensitivity in the detection of emboli, especially small emboli at a subsegmental level or in more distal vessels (13,14) and support prognosis determination and monitoring of anticoagulation therapy effectiveness (15).The most common technique used to generate these maps is dual-energy CT (16,17). However, this requires dedicated hardware. On the other hand, subtraction CT requires motion correction software but no additional hardware, making it easier to adopt and less costly to
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